强迫症和广泛性焦虑障碍的强迫症状:发生及相关性

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Anna Citkowska-Kisielewska, Krzysztof Rutkowski, Michał Mielimąka, Jerzy A Sobański, Edyta Dembińska
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引用次数: 7

摘要

目的:由于强迫症(OCDs)及其伴发焦虑症的异质性,我们调查了诊断为强迫症或广泛性焦虑症(GAD)的患者报告的强迫症和强迫症状的患病率、严重程度和相关性。方法:回顾性研究两组患者,一组为76例强迫症患者(按第十版国际疾病及相关健康问题统计分类(ICD-10) F42),另一组为186例广泛性焦虑症患者(按ICD-10 F41.1),均在日间病房就诊。基于症状检查表90-修订版(SCL-90-R)的症状问卷“O”被用来评估强迫、强迫和焦虑症状。分析考虑了性别和是否存在认知功能障碍(使用Bender Benton视觉保留和Bender格式塔测试进行评估)对正在调查的关联的影响。结果:我们观察到强迫症组比广泛性焦虑症组更普遍和更强烈地表达强迫和强迫症状。然而,几乎所有的广泛性焦虑症患者(94%)都证实存在一些强迫症状。该研究揭示了强迫症和广泛性焦虑症患者在强迫症和强迫行为方面的差异。在强迫症组中,强迫和强迫的严重程度之间没有明显的相关性,而在广泛性焦虑症组中,这些症状的严重程度之间存在显著的正相关。在广泛性焦虑症和强迫症两组中,更强烈的强迫症状都伴随着焦虑症状的严重程度的增加(这种影响在强迫症状中比在强迫症状中更明显)。结论:本研究揭示广泛性焦虑症患者常伴有强迫症状,这在常规精神科检查中可能无法发现。广泛性焦虑症患者的强迫症状可能与强迫症患者的强迫症状结构不同。这项研究的结果表明,强迫症的诊断比强迫症更具体。强迫性行为,如与秩序和对称需求相关的数数,可能与某些认知功能障碍和男性性别有关,这一发现需要进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Obsessive-Compulsive Symptoms in Obsessive-Compulsive Disorder and in Generalized Anxiety Disorder: Occurrence and Correlations.

Objective: Because of the heterogeneity of obsessive-compulsive disorders (OCDs) and their co-occurrence with anxiety disorders, we investigated the prevalence, severity, and correlations between obsessive and compulsive symptoms reported by patients diagnosed with OCD or generalized anxiety disorder (GAD).

Methods: A retrospective study was conducted in 2 groups of patients: 76 patients diagnosed with OCD [F42 according to the 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10)], and 186 patients diagnosed with GAD (F41.1 according to ICD-10), who had presented for therapy at the day ward. The Symptom Questionnaire "O," based on the Symptom Checklist 90-Revised (SCL-90-R) questionnaire, was used to assess obsessive, compulsive, and anxiety symptoms. The analysis took into account the impact of sex and the presence or absence of cognitive dysfunction (as assessed using the Bender Benton Visual Retention and Bender-Gestalt tests) on the associations being investigated.

Results: We observed that obsessive and compulsive symptoms were more prevalent and more strongly expressed in the group with OCD than in the group with GAD. However, almost all patients with GAD (94%) confirmed the presence of some obsessive-compulsive symptoms. The study revealed differences in correlations with obsessions and compulsions between the OCD and GAD groups. In the group with OCD, no significant correlation between the severity of obsessions and compulsions was identified, whereas in the group with GAD, a significant positive correlation was found between the severity of those symptoms. In both the GAD and OCD groups, a greater intensity of obsessive-compulsive symptoms was accompanied by an increase in the severity of anxiety symptoms (with this effect noted to a greater extent with obsessions than compulsions).

Conclusions: The study revealed that patients with GAD often have coexisting obsessive-compulsive symptoms, which may not be identified during routine psychiatric examination. Obsessive-compulsive symptoms observed in patients with GAD may show a different structure than obsessive-compulsive symptoms in patients with OCD. The results of this study suggest that compulsions are more specific for the diagnosis of OCD than obsessions. Compulsions, such as counting related to the need for order and symmetry, may be associated with some cognitive dysfunctions and male sex, a finding that requires further research.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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