在一只雄性恒河猴(Macaca mulatta)身上发现疑似格林-巴瑞综合征。

Q2 Agricultural and Biological Sciences
Primate Biology Pub Date : 2017-03-07 eCollection Date: 2017-01-01 DOI:10.5194/pb-4-27-2017
Tamara Becker, Florian Pieper, David Liebetanz, Martina Bleyer, Annette Schrod, Kerstin Maetz-Rensing, Stefan Treue
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引用次数: 0

摘要

吉兰-巴罗综合征(GBS)是一种罕见的人类急性炎性多神经病变。它通常是感染后形成针对髓鞘的自身抗体,导致运动神经元和脑神经进行性和或多或少严重的瘫痪。死亡率低,60% %患者经强化治疗后完全康复。在动物身上,有一些疾病与GBS非常相似,但猴子身上的GBS病例似乎很少。在本病例报告中,描述了雄性恒河猴进行性四肢瘫痪的临床过程。临床、脑脊液(CSF)、神经电图(ENG)和肌电图(EMG)和病理结果显示症状与人类GBS非常相似。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Suspect Guillain-Barré syndrome in a male rhesus macaque (<i>Macaca mulatta</i>).

Suspect Guillain-Barré syndrome in a male rhesus macaque (<i>Macaca mulatta</i>).

Suspect Guillain-Barré syndrome in a male rhesus macaque (Macaca mulatta).

Guillain-Barré syndrome (GBS) is a rare, mainly acute inflammatory polyneuropathy in humans. It is frequently post-infectious with auto antibodies being formed against myelin sheaths, resulting in a progressive and more-or-less severe paralysis of the motor neuron and cranial nerves. Mortality is low and 60 % of the patients recover completely from the disease after intensive treatment. In animals, there are a few diseases that closely resemble GBS, but cases of GBS in monkeys seem to be scarce. In this case report, the clinical course of a progressive tetraplegia in a male rhesus macaque is described. Clinical, cerebrospinal fluid (CSF), electroneurography (ENG) and electromyography (EMG), and pathological findings revealed symptoms very similar to human GBS.

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来源期刊
Primate Biology
Primate Biology Agricultural and Biological Sciences-Animal Science and Zoology
CiteScore
1.90
自引率
0.00%
发文量
8
审稿时长
13 weeks
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