Charles Sylvester, Mysore Siddaiah Krishna, Jaya Sankar Rao, Adimoolam Chandrasekar
{"title":"从印度南部两个部落种群的完整有丝分裂基因组推断的mtDNA单倍群M的原位聚类。","authors":"Charles Sylvester, Mysore Siddaiah Krishna, Jaya Sankar Rao, Adimoolam Chandrasekar","doi":"10.1127/homo/2020/1144","DOIUrl":null,"url":null,"abstract":"<p><p>This study reports the mitochondrial DNA haplogroup M diversity in two tribal populations of South India. The aim of this study was to analyze and establish a mitochondrial profile to know the genetic origin and relatedness of people of India. MtDNA variability of the complete mitochondrial genome was analyzed by the Sanger sequencing method. Our results revealed novel sub-lineages of haplogroup: M2, M3, M6, M35, M65, and an M* lineage, indicating a deep <i>in-situ</i> origin and spread of haplogroup M lineages in India, shared with many tribal and caste populations.</p>","PeriodicalId":46714,"journal":{"name":"Homo-Journal of Comparative Human Biology","volume":null,"pages":null},"PeriodicalIF":0.7000,"publicationDate":"2020-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"<i>In-situ</i> clustering of mtDNA haplogroup M inferred from complete mitogenomes of two tribal populations of Southern India.\",\"authors\":\"Charles Sylvester, Mysore Siddaiah Krishna, Jaya Sankar Rao, Adimoolam Chandrasekar\",\"doi\":\"10.1127/homo/2020/1144\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study reports the mitochondrial DNA haplogroup M diversity in two tribal populations of South India. The aim of this study was to analyze and establish a mitochondrial profile to know the genetic origin and relatedness of people of India. MtDNA variability of the complete mitochondrial genome was analyzed by the Sanger sequencing method. Our results revealed novel sub-lineages of haplogroup: M2, M3, M6, M35, M65, and an M* lineage, indicating a deep <i>in-situ</i> origin and spread of haplogroup M lineages in India, shared with many tribal and caste populations.</p>\",\"PeriodicalId\":46714,\"journal\":{\"name\":\"Homo-Journal of Comparative Human Biology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2020-02-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Homo-Journal of Comparative Human Biology\",\"FirstCategoryId\":\"90\",\"ListUrlMain\":\"https://doi.org/10.1127/homo/2020/1144\",\"RegionNum\":4,\"RegionCategory\":\"社会学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ANTHROPOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Homo-Journal of Comparative Human Biology","FirstCategoryId":"90","ListUrlMain":"https://doi.org/10.1127/homo/2020/1144","RegionNum":4,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ANTHROPOLOGY","Score":null,"Total":0}
In-situ clustering of mtDNA haplogroup M inferred from complete mitogenomes of two tribal populations of Southern India.
This study reports the mitochondrial DNA haplogroup M diversity in two tribal populations of South India. The aim of this study was to analyze and establish a mitochondrial profile to know the genetic origin and relatedness of people of India. MtDNA variability of the complete mitochondrial genome was analyzed by the Sanger sequencing method. Our results revealed novel sub-lineages of haplogroup: M2, M3, M6, M35, M65, and an M* lineage, indicating a deep in-situ origin and spread of haplogroup M lineages in India, shared with many tribal and caste populations.
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