Grace Yoon, Wenxin Jiang, Lei Liu, Ya-Chen Tina Shih
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Simple Quasi-Bayes Approach for Modeling Mean Medical Costs.
AbstractSeveral statistical issues associated with health care costs, such as heteroscedasticity and severe skewness, make it challenging to estimate or predict medical costs. When the interest is modeling the mean cost, it is desirable to make no assumption on the density function or higher order moments. Another challenge in developing cost prediction models is the presence of many covariates, making it necessary to apply variable selection methods to achieve a balance of prediction accuracy and model simplicity. We propose Spike-or-Slab priors for Bayesian variable selection based on asymptotic normal estimates of the full model parameters that are consistent as long as the assumption on the mean cost is satisfied. In addition, the scope of model searching can be reduced by ranking the Z-statistics. This method possesses four advantages simultaneously: robust (due to avoiding assumptions on the density function or higher order moments), parsimonious (feature of variable selection), informative (due to its Bayesian flavor, which can compare posterior probabilities of candidate models) and efficient (by reducing model searching scope with the use of Z-ranking). We apply this method to the Medical Expenditure Panel Survey dataset.
期刊介绍:
The International Journal of Biostatistics (IJB) seeks to publish new biostatistical models and methods, new statistical theory, as well as original applications of statistical methods, for important practical problems arising from the biological, medical, public health, and agricultural sciences with an emphasis on semiparametric methods. Given many alternatives to publish exist within biostatistics, IJB offers a place to publish for research in biostatistics focusing on modern methods, often based on machine-learning and other data-adaptive methodologies, as well as providing a unique reading experience that compels the author to be explicit about the statistical inference problem addressed by the paper. IJB is intended that the journal cover the entire range of biostatistics, from theoretical advances to relevant and sensible translations of a practical problem into a statistical framework. Electronic publication also allows for data and software code to be appended, and opens the door for reproducible research allowing readers to easily replicate analyses described in a paper. Both original research and review articles will be warmly received, as will articles applying sound statistical methods to practical problems.