[主动脉壁血栓]。

Juliana Varino, Roger Rodrigues, Bárbara Pereira, Mário Moreira, Óscar Gonçalves
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引用次数: 0

摘要

在没有动脉瘤或动脉粥样硬化的情况下,主动脉壁血栓是一种罕见的临床发现,但它是非心源性栓塞的重要来源,诊断困难,并发症发生率高,包括死亡率高。它似乎更常发生在年轻人通常与潜在的血栓形成障碍。随着高分辨率成像技术的日益普及,无症状的附壁血栓成为越来越常见的发现,但其栓塞的可能性或最佳治疗方法仍存在争议。非动脉粥样硬化性主动脉壁上血栓的处理是一个挑战,因为没有可用的指南,应该个体化。治疗方法应包括主动脉壁血栓的三个方面:原发疾病抗凝治疗、手术取栓解决栓塞并发症和血管内/经典手术排除主动脉血栓。历史上,治疗性抗凝被认为是一线治疗,对于血栓移动、复发性栓塞和抗凝禁忌症,保留手术干预。然而,它与25-50%的栓塞复发率,35%的血栓持续性和高达31%的继发性主动脉手术相关。最近的数据表明,在可行的情况下,血管内覆盖主动脉血栓似乎是一种有效和安全的手术,复发率和再栓塞率低。在本文中,我们回顾了有关这一主题的已发表的文献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Aortic mural thrombus].

Aortic mural thrombus is a rare clinical finding in the absence of aneurysm or atherosclerosis but an important source of noncardiogenic emboli with a difficult diagnosis and a high rate of complications, including high mortality. It appears to occur more frequently in young adults usually with underlying pro-thrombotic disorder. With the increasing use of high resolution imaging, the asymptomatic mural thrombus became an increasingly frequent finding, but its potential for embolization or the best treatment are still a matter of debate. The management of mural thrombus in non-atherosclerotic aorta represents a challenge because no guidelines are available, and should be individualized. The therapeutic approach should include the triple aspects of aortic mural thrombus: primary disease anticoagulation treatment, surgical thrombectomy to solve embolic complications and endovascular/classical surgery to exclude the thrombus from the aorta. Historically therapeutic anticoagulation was proposed as first-line therapy and surgical intervention was reserved for mobile thrombus, recurrent embolism and contraindication for anticoagulation. However, it is associated with a 25-50% embolic recurrence rate, thrombus persistence in 35% and secondary aortic surgery in up to 31% of the cases. Recent data suggest that endovascular coverage of the aortic thrombus, when feasible, appears to be an effective and safe procedure with a low recurrence and re-embolization rates. In this article we review the published literature concerning this topic.

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