多尺度随机空间基因网络最高范数中的大数定律。

IF 1.2 4区 数学 Q4 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Arnaud Debussche, Mac Jugal Nguepedja Nankep
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引用次数: 5

摘要

研究了多尺度随机空间基因网络的渐近行为。多尺度法考虑了分子间丰度的差异,在介观水平上捕捉了稀有物种的动态。引入了稀有物质反应的空间相关性假设,得到了一个新的大数定律。根据尺度,整个系统分为两个不同但耦合的动力学部分。高尺度分量收敛于通常的空间模型,即偏微分方程的解,而低尺度分量收敛于通常的齐次模型,即常微分方程的解。比较是在最高规范中进行的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Law of Large Numbers in the Supremum Norm for a Multiscale Stochastic Spatial Gene Network.

We study the asymptotic behavior of multiscale stochastic spatial gene networks. Multiscaling takes into account the difference of abundance between molecules, and captures the dynamic of rare species at a mesoscopic level. We introduce an assumption of spatial correlations for reactions involving rare species and a new law of large numbers is obtained. According to the scales, the whole system splits into two parts with different but coupled dynamics. The high scale component converges to the usual spatial model which is the solution of a partial differential equation, whereas the low scale component converges to the usual homogeneous model which is the solution of an ordinary differential equation. Comparisons are made in the supremum norm.

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来源期刊
International Journal of Biostatistics
International Journal of Biostatistics MATHEMATICAL & COMPUTATIONAL BIOLOGY-STATISTICS & PROBABILITY
CiteScore
2.10
自引率
8.30%
发文量
28
审稿时长
>12 weeks
期刊介绍: The International Journal of Biostatistics (IJB) seeks to publish new biostatistical models and methods, new statistical theory, as well as original applications of statistical methods, for important practical problems arising from the biological, medical, public health, and agricultural sciences with an emphasis on semiparametric methods. Given many alternatives to publish exist within biostatistics, IJB offers a place to publish for research in biostatistics focusing on modern methods, often based on machine-learning and other data-adaptive methodologies, as well as providing a unique reading experience that compels the author to be explicit about the statistical inference problem addressed by the paper. IJB is intended that the journal cover the entire range of biostatistics, from theoretical advances to relevant and sensible translations of a practical problem into a statistical framework. Electronic publication also allows for data and software code to be appended, and opens the door for reproducible research allowing readers to easily replicate analyses described in a paper. Both original research and review articles will be warmly received, as will articles applying sound statistical methods to practical problems.
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