特应性皮炎治疗标准在新兴靶向治疗开始前的比较。

IF 2.4
Journal of Drug Assessment Pub Date : 2019-06-10 eCollection Date: 2019-01-01 DOI:10.1080/21556660.2019.1619569
Elżbieta Kowalska-Olędzka, Magdalena Czarnecka, Anna Baran
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引用次数: 6

摘要

特应性皮炎(AD)是一种慢性炎症性疾病,主要存在于儿科人群中。治疗通常由各种医学专家监督,包括初级保健医生、过敏症专家和皮肤科医生。这种疾病管理上的差异允许由受监督的医生对患者实施各种治疗方法。本文涵盖了该疾病的病因学,并总结了2017年欧洲药品管理局(EMA)和美国联邦药物管理局(FDA)注册dupilumab之前选定国家的皮肤病治疗标准。在最近的靶向治疗(小分子和生物制剂)发展之前,阿尔茨海默病的治疗标准多年来保持不变,在特定地理和经济区域的一组样本国家中存在广泛的相似性。现有的和流行的治疗方案可分为三大类:非药物、药物和系统干预。原则上,他们的处方是由疾病严重程度和既往治疗史决定的。然而,靶向治疗的进展可能会改变阿尔茨海默病的管理指南和医疗标准。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of treatment standards in Atopic Dermatitis management across selected geographies prior to emerging targeted therapies onset.

Atopic Dermatitis (AD) is a chronic inflammatory disease persisting predominantly in the pediatric population. Treatment is generally supervised by various medical specialists, including primary care practitioners, allergists, and dermatologists. This divergence in disease management allows various therapeutic approaches to be administered to patients by supervised physicians. This article covers etiology of the disease and summarizes dermatologic treatment standards of selected countries binding prior to the registration of dupilumab by both the European Medicines Agency (EMA) and Federal Drug Administration (FDA) in 2017. Before recent development in targeted therapies (small molecules and biologic agents), standards in AD treatment remained unchanged for years with extensive similarities across a sample group of countries in particular geographic and economic regions. The spectrum of available and popular therapeutic options can be categorized into three dominating groups: non-pharmacologic, pharmacologic, and systemic interventions. Their prescription, in principle, was historically driven by disease severity and previous treatment history. However, advances in targeted therapies may change AD management guidelines and medical care standards.

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来源期刊
Journal of Drug Assessment
Journal of Drug Assessment PHARMACOLOGY & PHARMACY-
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