Radical addition/spirocyclization cascade of tryptamine-derived isocyanides with aryl boronic acids: efficient access to spiroindoline derivatives†

An efficient Mn(iii)-promoted cascade reaction of tryptamine-derived isocyanides with arylboronic acids for accessing spiroindoline derivatives is described. The reaction proceeds via a radical addition/spirocyclization pathway, providing spiroindolines in good yields under mild conditions.