通过炔酰胺环化形成七元环。

IF 1.7 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Monatshefte Fur Chemie Pub Date : 2019-01-01 Epub Date: 2018-11-16 DOI:10.1007/s00706-018-2320-x

Bogdan R Brutiu, Wilhelm Andrei Bubeneck, Olivera Cvetkovic, Jing Li, Nuno Maulide

引用次数: 0

摘要

摘要：介绍了一种布氏酸催化的选择性炔酰胺环化反应。该反应通过酮亚胺中间体进行，并能制备七元环烯酰胺产物。机理研究发现了一种不寻常的产物抑制行为：

本文章由计算机程序翻译，如有差异，请以英文原文为准。

On the formation of seven-membered rings by arene-ynamide cyclization.

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On the formation of seven-membered rings by arene-ynamide cyclization.

Abstract: A Brønsted acid-catalyzed selective arene-ynamide cyclization is described. This reaction proceeds via a keteniminium intermediate and enables the preparation of seven-membered ring enamide products. Mechanistic studies uncover an unusual product inhibition behavior.

Graphical abstract:

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来源期刊

Monatshefte Fur Chemie 化学-化学综合

CiteScore

3.70

自引率

5.60%

发文量

116

审稿时长

3.3 months

期刊介绍： "Monatshefte für Chemie/Chemical Monthly" was originally conceived as an Austrian journal of chemistry. It has evolved into an international journal covering all branches of chemistry. Featuring the most recent advances in research in analytical chemistry, biochemistry, inorganic, medicinal, organic, physical, structural, and theoretical chemistry, Chemical Monthly publishes refereed original papers and a section entitled "Short Communications". Reviews, symposia in print, and issues devoted to special fields will also be considered.