O V Martynova, G V Portnova, V V Balaev, A M Ivanitsky
{"title":"[健康受试者与言语障碍患者言语与空间思维脑活动的比较分析]。","authors":"O V Martynova, G V Portnova, V V Balaev, A M Ivanitsky","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>We analyzed the specific brain activity, measured by fMRI in spatial and verbal tasks, in 15 healthy sub- jects and in 9 patients with dysarthria or mild sensorimotor aphasia. In healthy participants, verbal thinking was characterized by activation in Brodmann area 19 and Broca area while specific activation for spatial thinking was observed in bilateral temporal-occipital-parietal areas, left insula, left visual fields 17 and 18. In patients with impaired speech, this distribution of networks specific to a particular type of task underwent significant changes with deactivation of the brain areas, as compared to healthy subjects. Despite the absence of clinical manifestations of cognitive impairment, the average time .to solve verbal tasks was significantly higher, and the percentage of correct answers was less in patients as compared to these values for a group of healthy subjects.</p>","PeriodicalId":49337,"journal":{"name":"Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I P Pavlova","volume":"66 3","pages":"313-326"},"PeriodicalIF":0.2000,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Comparative Analysis of the Brain Activity during Verbal and Spatial Thinking in Healthy Subjects and Patients with Speech Disorders].\",\"authors\":\"O V Martynova, G V Portnova, V V Balaev, A M Ivanitsky\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We analyzed the specific brain activity, measured by fMRI in spatial and verbal tasks, in 15 healthy sub- jects and in 9 patients with dysarthria or mild sensorimotor aphasia. In healthy participants, verbal thinking was characterized by activation in Brodmann area 19 and Broca area while specific activation for spatial thinking was observed in bilateral temporal-occipital-parietal areas, left insula, left visual fields 17 and 18. In patients with impaired speech, this distribution of networks specific to a particular type of task underwent significant changes with deactivation of the brain areas, as compared to healthy subjects. Despite the absence of clinical manifestations of cognitive impairment, the average time .to solve verbal tasks was significantly higher, and the percentage of correct answers was less in patients as compared to these values for a group of healthy subjects.</p>\",\"PeriodicalId\":49337,\"journal\":{\"name\":\"Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I P Pavlova\",\"volume\":\"66 3\",\"pages\":\"313-326\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2016-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I P Pavlova\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I P Pavlova","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
[Comparative Analysis of the Brain Activity during Verbal and Spatial Thinking in Healthy Subjects and Patients with Speech Disorders].
We analyzed the specific brain activity, measured by fMRI in spatial and verbal tasks, in 15 healthy sub- jects and in 9 patients with dysarthria or mild sensorimotor aphasia. In healthy participants, verbal thinking was characterized by activation in Brodmann area 19 and Broca area while specific activation for spatial thinking was observed in bilateral temporal-occipital-parietal areas, left insula, left visual fields 17 and 18. In patients with impaired speech, this distribution of networks specific to a particular type of task underwent significant changes with deactivation of the brain areas, as compared to healthy subjects. Despite the absence of clinical manifestations of cognitive impairment, the average time .to solve verbal tasks was significantly higher, and the percentage of correct answers was less in patients as compared to these values for a group of healthy subjects.