[CKD-MBD和心血管疾病]

Hideki Fujii
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引用次数: 2

摘要

心血管疾病(CVD)是慢性肾脏疾病患者死亡的重要原因,多种因素在CVD的进展中起作用。在各种因素中,矿物质骨紊乱是近年来研究的热点。磷酸盐是一个重要的因素,因为它不仅直接影响心血管系统,也间接影响心血管系统。磷酸盐可以影响血清和细胞中甲状旁腺激素、成纤维细胞生长因子23和活性维生素D的水平,从而导致心血管疾病的进展。因此,了解心血管疾病进展的机制并考虑控制矿物质骨紊乱是至关重要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[CKD-MBD and cardiovascular disease.]

Cardiovascular disease(CVD)is a crucial cause of death in patients with chronic kidney disease and various factors play a role in the progression of CVD. Among the various factors, mineral bone disorder has been focused on in recent year. Phosphate is an important factor because it affects cardiovascular system not only directly but also indirectly. Phosphate can influence the serum and cellar levels of parathyroid hormone, fibroblast growth factor 23, and active vitamin D and thereby leading to the progression of CVD. Thus, it is essential to understand the mechanisms of CVD progression and think about a control of mineral bone disorder.

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