Jennifer I Etcheson, Chukwuweike U Gwam, Nicole E George, Naval Walia, Christophe Jerjian, Ga-Ram Han, Sana Virani, Seth J Miller, Ronald E Delanois
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An independent samples <i>t</i> -test and Chi-square analysis was conducted to assess continuous and categorical variables respectively. <b>Results</b> Smokers experienced a nonsignificantly increased pain intensity (198.1 vs. 185.7; <i>p</i> = 0.063). Smokers demonstrated significantly higher opioid consumption in both immediate postoperative (65.9 vs. 59.3 mEq; <i>p</i> = 0.045) and 90 days postoperative periods (619.9 vs. 458.9 mEq; <i>p</i> = 0.029). <b>Conclusion</b> Our study demonstrated a nonsignificantly increased pain intensity, and (in both the immediate and 90 days postoperative periods) a significantly higher opioid consumption following THA in patients who smoke cigarettes. This may be due to a relatively small effect size, warranting the need for larger prospective studies. Nevertheless, arthroplasty surgeons should encourage preoperative smoking cessation and alternative nonopioid analgesics to smoking patients receiving THA. <b>Level of Evidence</b> This is a level III, retrospective cohort study.</p>","PeriodicalId":37852,"journal":{"name":"Joints","volume":"6 3","pages":"157-160"},"PeriodicalIF":0.0000,"publicationDate":"2018-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0038-1673405","citationCount":"13","resultStr":"{\"title\":\"Opiate Pain Medication Consumption in Cigarette Smokers following Total Hip Arthroplasty.\",\"authors\":\"Jennifer I Etcheson, Chukwuweike U Gwam, Nicole E George, Naval Walia, Christophe Jerjian, Ga-Ram Han, Sana Virani, Seth J Miller, Ronald E Delanois\",\"doi\":\"10.1055/s-0038-1673405\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Purpose</b> The purpose of the present study was to assess perception of pain and pain management in smokers versus nonsmokers who received a total hip arthroplasty (THA). <b>Methods</b> Patients who underwent THA from 2010 to 2016 were propensity score matched 1:1 based on race, body mass index, age, and sex. This yielded 124 smokers and 124 nonsmokers. Pain intensity was quantified using area under the curve for visual analog scale pain scores. Opioid consumption was determined using a morphine milliequivalent (mEq) conversion algorithm. An independent samples <i>t</i> -test and Chi-square analysis was conducted to assess continuous and categorical variables respectively. <b>Results</b> Smokers experienced a nonsignificantly increased pain intensity (198.1 vs. 185.7; <i>p</i> = 0.063). Smokers demonstrated significantly higher opioid consumption in both immediate postoperative (65.9 vs. 59.3 mEq; <i>p</i> = 0.045) and 90 days postoperative periods (619.9 vs. 458.9 mEq; <i>p</i> = 0.029). <b>Conclusion</b> Our study demonstrated a nonsignificantly increased pain intensity, and (in both the immediate and 90 days postoperative periods) a significantly higher opioid consumption following THA in patients who smoke cigarettes. 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引用次数: 13
摘要
本研究的目的是评估吸烟者与接受全髋关节置换术(THA)的非吸烟者的疼痛感知和疼痛管理。方法2010 - 2016年接受人工髋关节置换术的患者按种族、体重指数、年龄、性别进行倾向评分1:1匹配。结果得出124名吸烟者和124名不吸烟者。疼痛强度采用视觉模拟量表疼痛评分曲线下面积量化。使用吗啡毫当量(mEq)转换算法确定阿片类药物消费量。对连续变量和分类变量分别进行独立样本t检验和卡方分析。结果吸烟者的疼痛强度无显著增加(198.1 vs. 185.7;P = 0.063)。术后两组吸烟者的阿片类药物消耗量均显著增加(65.9 mEq vs. 59.3 mEq;p = 0.045)和术后90天(619.9 vs. 458.9 mEq;P = 0.029)。结论:我们的研究表明吸烟的患者THA术后疼痛强度无明显增加,并且(在术后即刻和术后90天)阿片类药物的消耗明显增加。这可能是由于相对较小的效应量,因此需要进行更大规模的前瞻性研究。然而,关节置换术医生应鼓励接受THA的吸烟患者术前戒烟并使用非阿片类镇痛药。证据水平这是一项III级回顾性队列研究。
Opiate Pain Medication Consumption in Cigarette Smokers following Total Hip Arthroplasty.
Purpose The purpose of the present study was to assess perception of pain and pain management in smokers versus nonsmokers who received a total hip arthroplasty (THA). Methods Patients who underwent THA from 2010 to 2016 were propensity score matched 1:1 based on race, body mass index, age, and sex. This yielded 124 smokers and 124 nonsmokers. Pain intensity was quantified using area under the curve for visual analog scale pain scores. Opioid consumption was determined using a morphine milliequivalent (mEq) conversion algorithm. An independent samples t -test and Chi-square analysis was conducted to assess continuous and categorical variables respectively. Results Smokers experienced a nonsignificantly increased pain intensity (198.1 vs. 185.7; p = 0.063). Smokers demonstrated significantly higher opioid consumption in both immediate postoperative (65.9 vs. 59.3 mEq; p = 0.045) and 90 days postoperative periods (619.9 vs. 458.9 mEq; p = 0.029). Conclusion Our study demonstrated a nonsignificantly increased pain intensity, and (in both the immediate and 90 days postoperative periods) a significantly higher opioid consumption following THA in patients who smoke cigarettes. This may be due to a relatively small effect size, warranting the need for larger prospective studies. Nevertheless, arthroplasty surgeons should encourage preoperative smoking cessation and alternative nonopioid analgesics to smoking patients receiving THA. Level of Evidence This is a level III, retrospective cohort study.
期刊介绍:
Joints is the official publication of SIGASCOT (Italian Society of the Knee, Arthroscopy, Sports Traumatology, Cartilage and Orthopaedic Technology). As an Open Acccess journal, it publishes papers on clinical and basic research, review articles, technical notes, case reports, and editorials about the latest developments in knee surgery, arthroscopy, sports traumatology, cartilage, orthopaedic technology, upper limb, and related rehabilitation. Letters to the Editor and comments on the journal''s content are always welcome.