重复经颅磁刺激(rTMS)治疗抑郁症

Satoshi Ukai
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引用次数: 0

摘要

在日本,rTMS治疗抑郁症的临床应用正在取得进展。基于大规模随机对照试验的成功结果,美国FDA于2008年批准了一种rTMS设备,目前有四种rTMS设备被批准并在几个国家和欧盟使用。随机对照试验和现实世界自然观察性研究的荟萃分析结果显示,对难治性抑郁症有有益的作用。rTMS通常具有良好的耐受性和安全性,但有癫痫发作的风险,估计发病率约为千分之一。对于那些无法从最初的抗抑郁药物中获益的人,rTMS被认为是一种有效的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[rTMS (Repetitive Transcranial Magnetic Stimulation) for the Treatment of Depression].

The clinical introduction of rTMS for the treatment of depression is now progressing in Japan. On the basis of the successful results of a large-scale RCT, the US FDA approved an rTMS device in 2008, and four rTMS devices are now approved and used in several countries and the EC. The results of the meta-analysis of RCTs and the real-world naturalistic observa- tional studies show beneficial effects on treatment-resistant depression. The rTMS is generally well-tolerated and safe, but has a risk of seizure, with an estimated rate of approximately one in 1,000 patients. The rTMS is thought to be an effective treatment for those unable to benefit from initial antidepressant medication.

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