[切尔诺贝利事故前后(回忆录,研究假设)]。

I E Vorobtsova
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引用次数: 0

摘要

文章的第一部分介绍了1970- 80年代辐照动物(果蝇、小鼠、大鼠)后代的研究结果。结果发现,该子代除存在严重的遗传失调外,还存在与晚期体细胞辐射效应相似的非靶遗传辐射效应(基因组不稳定、癌症风险增加、健康受损)。提出了电离辐射的躯体效应和遗传效应致病性质相似的假说。父母辐照对人类和动物的影响的比较使我们有理由提出,在后代中观察到的严重疾病(死胎、出生缺陷等)的频率取决于一个物种的生殖潜力。在文章的第二部分,回顾了作者在1987年切尔诺贝利的工作。最后一部分专门描述切尔诺贝利事故后在各种国家和国际项目框架内取得的主要成果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Before and after Chernobyl Accident (Memoirs, Researches Hypotheses)].

In the first part of the article the results of studies performed in the 1970-1980s on the progeny of irradiated animals (drosophila, mouse, rat) are presented. It was found that except severe disorders in this progeny named non target genetic radiation effects were observed (genome instability, increased cancer risk, impaired fitness) which were similar to the late somatic radiation effects. The hypothesis on the likeness of pathogenic nature of somatic and genetic effects of ionizing radiation was proposed. Comparison of effects of parental irradiation in humans and animals gave reason to propose that the frequency of severe disorders observed in the progeny (stillbirth, birth defects etc.) depends on the reproductive potential of a species. In the second part of the article the reminiscences on the author's work in Chernobyl in 1987 are presented. The last part is devoted to description of the main results, obtained in the post Chernobyl period in the frames of various national and international projects.

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