肥胖和炎症。

IF 2.2 4区 医学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Jacek Karczewski, Ewelina Śledzińska, Alina Baturo, Izabela Jończyk, Aleksander Maleszko, Paweł Samborski, Beata Begier-Krasińska, Agnieszka Dobrowolska
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引用次数: 140

摘要

肥胖症的流行率最近急剧增加,并导致各种病理状况的流行率增加,包括2型糖尿病、非酒精性脂肪性肝病、哮喘、各种类型的癌症、心血管和神经退行性疾病等。越来越多的证据表明,脂肪组织的局部炎症反过来又促进了全身性低级别炎症,这是促成这些病理发展的主要力量。需要更好地了解肥胖引起的脂肪组织炎症背后的潜在机制,以制定有效的治疗或预防策略。本综述旨在介绍与肥胖相关的脂肪组织炎症的最新知识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Obesity and inflammation.

The prevalence of obesity has recently increased dramatically and has contributed to the increasing prevalence of various pathological conditions, including type 2 diabetes mellitus, nonalcoholic fatty liver disease, asthma, various types of cancer, cardiovascular and neurodegenerative diseases, and others. Accumulating evidence points to localized inflammation in adipose tissue, which, in turn, promotes systemic low-grade inflammation as a primary force contributing to the development of these pathologies. A better understanding of the underlying mechanisms behind obesity-induced adipose tissue inflammation is required to develop effective therapeutic or prophylactic strategies. This review is aimed to present the current knowledge of adipose tissue inflammation associated with obesity.

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来源期刊
European cytokine network
European cytokine network 生物-免疫学
CiteScore
5.70
自引率
0.00%
发文量
5
审稿时长
6 months
期刊介绍: The journal that brings together all areas of work involving cytokines. European Cytokine Network is an electronic journal that publishes original articles and abstracts every quarter to provide an essential bridge between researchers and clinicians with an interest in this cutting-edge field. The journal has become a must-read for specialists in the field thanks to its swift publication and international circulation. The journal is referenced in several databases, including Medline, which is testament to its scientific quality.
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