开放性穿透性脊髓创伤伴椎体通道生物相容性异物持久存在的模拟模型。创伤后痉挛综合征。

Klinichna khirurgiia Pub Date : 2016-10-01
V I Tsymbalyuk, V V Medvedyev, N Ya Grydina, Yu Yu Senchyk, M M Таtarchuk, N G Draguntsova, S M Dychko, T I Petriv
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引用次数: 0

摘要

采用wistarline成年雄性大鼠开放性穿透性脊髓(SC)模型,研究了生物相容性异物持久压迫下SC横断面半截后的创伤后痉挛综合征动力学。异物挤压受损的SC可增强痉挛综合征的形成,但不影响或限制剧烈疼痛综合征的发生。由于异物伸长引起的SC挤压减少及其体积减小,伴随着功能活动的正常上升和痉挛的减少。模拟创伤中运动系统传出链活性的变化与痉挛综合征的形成在损伤者和未损伤者的SC部位均有发生,其严重程度与创伤区异物的存在无关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A SIMULATION MODEL OF THE OPEN PENETRATING SPINAL CORD TRAUMA WITH DURABLE PERSISTENCE OF BIOCOMPATIBLE FOREIGN BODY OF THE VERTEBRAL COLUMN CHANNELL. SYNDROME OF POSTTRAUMATIC SPASTICITY.

Dynamics of the posttraumatic spasticity syndrome, a key component of spinal trauma, was investigated on simulation model of the open penetrating spinal cord (SC) trauma on adult male rats of aWistarline after half transection of the SC cross'section with its durable compression by biocompatible foreign body. Squeezing of the injured SC by foreign body potentiates formation of spasticity syndrome, and do not influence or restricts a severe pain syndrome occurrence. Reduction of the SC squeezing due to the foreign body elongation and reduction of its volume was accompanied by trustwor' thy rising of functional activity and the spasticity reduction in paretic extremity. Changes in activity of efferent chain of the movement system while formation of spasticity syn' drome in simulated trauma have occurred in both parts of SC ' in the injured one and in intact one as well, its severity did not correlate with presence of foreign body in zone of trauma.

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