V I Tsymbalyuk, V V Medvedyev, N Ya Grydina, Yu Yu Senchyk, M M Таtarchuk, N G Draguntsova, S M Dychko, T I Petriv
{"title":"开放性穿透性脊髓创伤伴椎体通道生物相容性异物持久存在的模拟模型。创伤后痉挛综合征。","authors":"V I Tsymbalyuk, V V Medvedyev, N Ya Grydina, Yu Yu Senchyk, M M Таtarchuk, N G Draguntsova, S M Dychko, T I Petriv","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Dynamics of the posttraumatic spasticity syndrome, a key component of spinal trauma,\nwas investigated on simulation model of the open penetrating spinal cord (SC) trauma\non adult male rats of aWistarline after half transection of the SC cross'section with its\ndurable compression by biocompatible foreign body. Squeezing of the injured SC by\nforeign body potentiates formation of spasticity syndrome, and do not influence or\nrestricts a severe pain syndrome occurrence. Reduction of the SC squeezing due to\nthe foreign body elongation and reduction of its volume was accompanied by trustwor'\nthy rising of functional activity and the spasticity reduction in paretic extremity. Changes\nin activity of efferent chain of the movement system while formation of spasticity syn'\ndrome in simulated trauma have occurred in both parts of SC ' in the injured one and in\nintact one as well, its severity did not correlate with presence of foreign body in zone of\ntrauma.</p>","PeriodicalId":32618,"journal":{"name":"Klinichna khirurgiia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A SIMULATION MODEL OF THE OPEN PENETRATING SPINAL\\nCORD TRAUMA WITH DURABLE PERSISTENCE \\nOF BIOCOMPATIBLE FOREIGN BODY OF THE VERTEBRAL\\nCOLUMN CHANNELL. \\nSYNDROME OF POSTTRAUMATIC SPASTICITY.\",\"authors\":\"V I Tsymbalyuk, V V Medvedyev, N Ya Grydina, Yu Yu Senchyk, M M Таtarchuk, N G Draguntsova, S M Dychko, T I Petriv\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Dynamics of the posttraumatic spasticity syndrome, a key component of spinal trauma,\\nwas investigated on simulation model of the open penetrating spinal cord (SC) trauma\\non adult male rats of aWistarline after half transection of the SC cross'section with its\\ndurable compression by biocompatible foreign body. Squeezing of the injured SC by\\nforeign body potentiates formation of spasticity syndrome, and do not influence or\\nrestricts a severe pain syndrome occurrence. Reduction of the SC squeezing due to\\nthe foreign body elongation and reduction of its volume was accompanied by trustwor'\\nthy rising of functional activity and the spasticity reduction in paretic extremity. Changes\\nin activity of efferent chain of the movement system while formation of spasticity syn'\\ndrome in simulated trauma have occurred in both parts of SC ' in the injured one and in\\nintact one as well, its severity did not correlate with presence of foreign body in zone of\\ntrauma.</p>\",\"PeriodicalId\":32618,\"journal\":{\"name\":\"Klinichna khirurgiia\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Klinichna khirurgiia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Klinichna khirurgiia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A SIMULATION MODEL OF THE OPEN PENETRATING SPINAL
CORD TRAUMA WITH DURABLE PERSISTENCE
OF BIOCOMPATIBLE FOREIGN BODY OF THE VERTEBRAL
COLUMN CHANNELL.
SYNDROME OF POSTTRAUMATIC SPASTICITY.
Dynamics of the posttraumatic spasticity syndrome, a key component of spinal trauma,
was investigated on simulation model of the open penetrating spinal cord (SC) trauma
on adult male rats of aWistarline after half transection of the SC cross'section with its
durable compression by biocompatible foreign body. Squeezing of the injured SC by
foreign body potentiates formation of spasticity syndrome, and do not influence or
restricts a severe pain syndrome occurrence. Reduction of the SC squeezing due to
the foreign body elongation and reduction of its volume was accompanied by trustwor'
thy rising of functional activity and the spasticity reduction in paretic extremity. Changes
in activity of efferent chain of the movement system while formation of spasticity syn'
drome in simulated trauma have occurred in both parts of SC ' in the injured one and in
intact one as well, its severity did not correlate with presence of foreign body in zone of
trauma.