开发类似人工手指的膝关节加载装置,促进骨骼健康。

Sandeep Korupolu, Stanley Chien, Hiroki Yokota, Sohel Anwar
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引用次数: 0

摘要

本研究介绍了一种创新的人工手指状装置的开发情况,该装置可在长骨末端提供特定位置的机械负荷,并诱导骨骼中的机械传导。骨细胞(如成骨细胞)是调节骨骼重塑的机械敏感细胞。当它们接受温和、周期性的机械负荷时,新骨的形成就会得到促进。拟议中的装置是一种欠驱动多指人造手,有 4 个手指,每个手指有两个指骨。这些手指由机械连杆连接,并通过蜗轮蜗杆传动机构进行操作。在三维打印技术的帮助下,主要使用塑料材料制作了一个原型装置。实验验证结果表明,该装置能够在所需频率下产生必要的力,适合刺激骨细胞和促进骨形成。建议在临床研究中对该装置进行测试,以确认其对患者的安全性和有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Development of an Artificial Finger-Like Knee Loading Device to Promote Bone Health.

Development of an Artificial Finger-Like Knee Loading Device to Promote Bone Health.

Development of an Artificial Finger-Like Knee Loading Device to Promote Bone Health.

Development of an Artificial Finger-Like Knee Loading Device to Promote Bone Health.

This study presents the development of an innovative artificial finger-like device that provides position specific mechanical loads at the end of the long bone and induces mechanotransduction in bone. Bone cells such as osteoblasts are the mechanosensitive cells that regulate bone remodelling. When they receive gentle, periodic mechanical loads, new bone formation is promoted. The proposed device is an under-actuated multi-fingered artificial hand with 4 fingers, each having two phalanges. These fingers are connected by mechanical linkages and operated by a worm gearing mechanism. With the help of 3D printing technology, a prototype device was built mostly using plastic materials. The experimental validation results show that the device is capable of generating necessary forces at the desired frequencies, which are suitable for the stimulation of bone cells and the promotion of bone formation. It is recommended that the device be tested in a clinical study for confirming its safety and efficacy with patients.

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