帕米膦酸钠治疗青年男性髋关节骨坏死。

Q4 Medicine

Open Rheumatology Journal Pub Date : 2018-08-29 eCollection Date: 2018-01-01 DOI:10.2174/1874312901812010125

A Lo Gullo, R Talotta, M Atteritano

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引用次数: 0

摘要

背景:髋关节无菌性骨坏死是一种临床实体，其中骨的坏死过程导致疼痛和进行性残疾。目的:帕米膦酸钠似乎能显著降低破骨细胞的激活，因此它只能在疾病的早期有用，延迟骨塌陷的时间。方法:27岁男性，每4周连续3天给予帕米膦酸钠治疗。结果:3个月后，患者回到对照组，临床状况明显改善，疼痛和运动障碍完全恢复，生活质量改善，对照组MRI结果证实了这一点。结论:我们报告了一例应用帕米膦酸盐45mg治疗髋关节无菌性骨坏死的成功病例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Pamidronate Treatment of Osteonecrosis of the Hip in Young Male.

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Pamidronate Treatment of Osteonecrosis of the Hip in Young Male.

Background: Aseptic osteonecrosis of the hip is a clinical entity in which the necrotic process of the bone leads to pain and progressive disability. Objective: Pamidronate seems to reduce drastically the activation of the osteoclasts so that it can be useful only in the early stage of the disease, delaying the time of bone collapsing. Method: A 27-years-old male was treated with pamidronate for three consecutive days every four weeks. Results: After three months the patient came back at control showing a marked improvement in clinical condition, referred full recover from pain and dysmotility with improvement of the quality of life, which was confirmed by the result of MRI he had for control. Conclusion: We reported a case of aseptic osteonecrosis of the hip which was successfully treated pamidronate at dosage of 45 mg.

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来源期刊

Open Rheumatology Journal Medicine-Rheumatology

CiteScore

0.80

自引率

0.00%

发文量

期刊介绍： ENTHAM Open publishes a number of peer-reviewed, open access journals. These free-to-view online journals cover all major disciplines of science, medicine, technology and social sciences. BENTHAM Open provides researchers a platform to rapidly publish their research in a good-quality peer-reviewed journal. All peer-reviewed accepted submissions meeting high research and ethical standards are published with free access to all.