材料对支架展开影响的计算机评估。

Georgia S Karanasiou, Nikolaos S Tachos, Antonios Sakellarios, Lampros K Michalis, Claire Conway, Elazer R Edelman, Dimitrios I Fotiadis
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引用次数: 1

摘要

冠状动脉支架是一种可扩展的支架,用于扩大闭塞的病变动脉并恢复血液流动。由于它们所暴露的应变和它们必须抵抗的力以及表面相互作用的重要性,材料性质占主导地位。事实上,商用支架之间的一个共同区别因素是它们的材料。一些性能要求与支架材料有关,包括部署后足够动脉支持的径向强度。本研究在三种有限元模型中研究了支架材料的影响,采用不同的支架制成:(i)钴铬(CoCr), (ii)不锈钢(SS316L)和(iii)铂铬(PtCr)。基于血管造影数据和血管内超声图像的融合,研究了患者特定动脉几何形状的部署。计算机模拟结果表明:(1)CoCr的von Mises应力最大,但所有支架的弯曲区域比直支架段的应力更高;(2)CoCr支架部署情况下存在更多的高动脉内应力区域;(3)各模型的动脉应力体积分布百分比无显著差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

<i>In silico</i> assessment of the effects of material on stent deployment.

<i>In silico</i> assessment of the effects of material on stent deployment.

<i>In silico</i> assessment of the effects of material on stent deployment.

In silico assessment of the effects of material on stent deployment.

Coronary stents are expandable scaffolds that are used to widen occluded diseased arteries and restore blood flow. Because of the strain they are exposed to and forces they must resist as well as the importance of surface interactions, material properties are dominant. Indeed, a common differentiating factors amongst commercially available stents is their material. Several performance requirements relate to stent materials including radial strength for adequate arterial support post-deployment. This study investigated the effect of the stent material in three finite element models using different stents made of: (i) Cobalt-Chromium (CoCr), (ii) Stainless Steel (SS316L), and (iii) Platinum Chromium (PtCr). Deployment was investigated in a patient specific arterial geometry, created based on a fusion of angiographic data and intravascular ultrasound images. In silico results show that: (i) the maximum von Mises stress occurs for the CoCr, however the curved areas of the stent links present higher stresses compared to the straight stent segments for all stents, (ii) more areas of high inner arterial stress exist in the case of the CoCr stent deployment, (iii) there is no significant difference in the percentage of arterial stress volume distribution among all models.

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