白藜芦醇未来研究方向。

Q3 Medicine

Nutrition and Healthy Aging Pub Date : 2018-06-15 DOI:10.3233/NHA-170035

Devin Wahl, Michel Bernier, Stephen J Simpson, Rafael de Cabo, David G Le Couteur

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引用次数: 20

摘要

白藜芦醇可以延长许多生物体的健康寿命和寿命。人们提出了几种不同的目标和作用机制来解释白藜芦醇对健康和长寿的有益影响，包括激活被称为sirtuins的蛋白质家族及其作为卡路里限制模拟物的作用。在这篇小型综述中，我们讨论了迄今为止在白藜芦醇领域的一些最新发现，并根据这些结果提出了未来研究的三个领域。

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Future directions of resveratrol research.

Resveratrol improves healthspan and lifespan in many organisms. Several different targets and mechanisms of action have been proposed to explain the beneficial effects of resveratrol on healthspan and longevity, including the activation of a family of proteins known as sirtuins and its action as a calorie restriction mimetic. In this mini-review, we discuss some of the most recent findings to date in the resveratrol field and suggest three areas of future research based on those results.

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来源期刊

Nutrition and Healthy Aging Agricultural and Biological Sciences-Food Science

CiteScore

1.70

自引率

0.00%

发文量

期刊介绍： Nutrition and Healthy Aging is an international forum for research on nutrition as a means of promoting healthy aging. It is particularly concerned with the impact of nutritional interventions on the metabolic and molecular mechanisms which modulate aging and age-associated diseases, including both biological responses on the part of the organism itself and its micro biome. Results emanating from both model organisms and clinical trials will be considered. With regards to the latter, the journal will be rigorous in only accepting for publication well controlled, randomized human intervention trials that conform broadly with the current EFSA and US FDA guidelines for nutritional clinical studies. The journal will publish research articles, short communications, critical reviews and conference summaries, whilst open peer commentaries will be welcomed.