利用LICHeE和BAMSE重建肿瘤系统发育树

Q1 Biochemistry, Genetics and Molecular Biology

Current protocols in bioinformatics Pub Date : 2018-05-16 DOI:10.1002/cpbi.49

Camir Ricketts, Victoria Popic, Hosein Toosi, Iman Hajirasouliha

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引用次数: 5

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Using LICHeE and BAMSE for Reconstructing Cancer Phylogenetic Trees

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Using LICHeE and BAMSE for Reconstructing Cancer Phylogenetic Trees

The reconstruction of cancer phylogeny trees and quantifying the evolution of the disease is a challenging task. LICHeE and BAMSE are two computational tools designed and implemented recently for this purpose. They both utilize estimated variant allele fraction of somatic mutations across multiple samples to infer the most likely cancer phylogenies. This unit provides extensive guidelines for installing and running both LICHeE and BAMSE. © 2018 by John Wiley & Sons, Inc.

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Current protocols in bioinformatics Biochemistry, Genetics and Molecular Biology-Biochemistry

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期刊介绍： With Current Protocols in Bioinformatics, it"s easier than ever for the life scientist to become "fluent" in bioinformatics and master the exciting new frontiers opened up by DNA sequencing. Updated every three months in all formats, CPBI is constantly evolving to keep pace with the very latest discoveries and developments.