[从无瓣Lepidium aptalum wild种子中提取的一种新的苯乙酰胺]。

药学学报 Pub Date : 2016-12-01

Li Meng, Xiao-ke Zheng, Zhi-guang Zhang, Jing-ke Zhang, Xuan Zhao, Yan-yun Yang, Xiao-lan Wang, Hai-xue Kuang, Wei-sheng Feng

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引用次数: 0

摘要

无瓣韭种子的化学成分。采用Diaion HP-20、Toyopearl HW-40、MCI Gel CHP-20、ODS、硅胶色谱和半制备高效液相色谱等色谱方法进行研究。从该植物中分离得到3个化合物，通过光谱数据和理化性质对其结构进行了鉴定，分别为lepidiumamide A(1)、顺式-desulfoglucotropaeolin(2)、反式-desulfoglucotropaeolin(3)。其中化合物1为新合成的苯乙酰胺，化合物2和3为首次从该植物中分离得到，构型也首次鉴定。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

[A new phenylacetamide from the seeds of Lepidium apetalum Willd].

The chemical constituents of the seeds of Lepidium apetalum Willd. were investigated using chromatographic methods, including Diaion HP-20, Toyopearl HW-40, MCI Gel CHP-20, ODS, silica gel chromatography and semi-preparative-HPLC. Three compounds were isolated and their structures were elucidated by spectral data and physicochemical properties, which were identified as lepidiumamide A (1), cis-desulfoglucotropaeolin(2), trans-desulfoglucotropaeolin (3). Among those, compound 1 is a new phenylacetamide, compound 2 and 3 were isolated from this plant for the first time, and their configurations were also identified for the first time.

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来源期刊

药学学报 Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： Acta Pharmaceutica Sinica B (APSB) is a bimonthly English peer-reviewed online journal in ScienceDirect, which publishes significant original research articles, communications and high quality reviews of recent advances. APSB encourages submissions from all areas of pharmaceutical sciences, including pharmacology, pharmaceutics, medicinal chemistry, natural products, pharmacognosy, pharmaceutical analysis and pharmacokinetics. APSB is a part of the series Acta Pharmaceutica Sinica, which was founded in 1953. The journal is co-published by Elsevier B.V., in association with the Institute of MateriaMedica, Chinese Academy of Medical Sciences and Chinese Pharmaceutical Association.