[结核分枝杆菌PhoP系统]。

微生物学报 Pub Date : 2017-04-04
Yuan Zhang, Jianping Xie
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引用次数: 0

摘要

PhoPR是结核分枝杆菌重要的双组分调控系统。PhoP作为一种反应调节因子参与细胞壁脂质生物合成和基因表达调控,对毒力至关重要。本文就PhoP的结构、功能及其在疫苗中的应用作一综述,并对有待解决的问题作一综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Mycobacterium tuberculosis PhoP system].

PhoPR is an important two-component regulatory system in Mycobacterium tuberculosis. PhoP is essential for virulence as a response regulator involved in cell wall lipid biosynthesis and regulation of gene expression. In this review, the structure, function and vaccine application of PhoP were summarized, as well as some questions that need to be solved.

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来源期刊
自引率
0.00%
发文量
7960
期刊介绍: Acta Microbiologica Sinica(AMS) is a peer-reviewed monthly (one volume per year)international journal,founded in 1953.It covers a wide range of topics in the areas of general and applied microbiology.The journal publishes original papers,reviews in microbiological science,and short communications describing unusual observations. Acta Microbiologica Sinica has been indexed in Index Copernicus (IC),Chemical Abstract (CA),Excerpt Medica Database (EMBASE),AJ of Viniti (Russia),Biological Abstracts (BA),Chinese Science Citation Database (CSCD),China National Knowledge Infrastructure(CNKI),Institute of Scientific and Technical Information of China(ISTIC),Chinese Journal Citation Report(CJCR),Chinese Biological Abstracts,Chinese Pharmaceutical Abstracts,Chinese Medical Abstracts and Chinese Science Abstracts.
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