卡里科指数是指导在全身麻醉下接受头颈部手术的患者术后需氧量的参数:一项横断面研究。

Q2 Medicine
Parnandi Bhaskar Rao, Manaswini Mangaraj, Preetam Mahajan, Swagata Tripathy, Neha Singh, Thenmozhi Mani, Sukdev Nayak
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引用次数: 0

摘要

背景和目的:肺功能的改变和随之而来的氧饱和度下降与麻醉时间的长短有关。因此,有必要在围手术期进行氧气监测和补充。但是,关于术后补氧的最佳指导参数以及与麻醉持续时间最相关的参数,目前还缺乏证据:方法:招募计划在全身麻醉下进行头颈部手术的成人患者。方法:招募计划在全身麻醉下进行头颈部手术的成人患者,分别在麻醉前和拔管后一小时采集两份桡动脉血液样本。主要结果指标为氧分压(PaO2)、饱和度(SpO2)、动脉血氧含量(CaO2)和卡里科指数(PaO2/FiO2)及其与麻醉持续时间的关系:112 名患者的数据显示,低氧血症发生率为 11.6%。我们观察到平均 CaO2 和血红蛋白浓度下降,但恢复时平均 PaO2 上升。复苏时的平均 PaO2/FiO2 下降了 225.65 ± 72.46 (95% CI 367.66, 83.64, p = 0.000),麻醉持续时间与复苏时 PaO2/FiO2 下降之间存在显著相关性(r = 0.2, p = 0.03),回归系数为 0.27 (95% CI 0.02, 0.50):卡里科指数被证明是围术期需要监测的最佳参数,可用于检测头颈部手术全身麻醉患者气体交换的变化。卡里科指数的下降与麻醉时间的长短呈正相关,尤其是当麻醉时间超过 150 分钟时。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The Carrico index is the parameter that guides the requirement of oxygen in the postoperative period in patients undergoing head and neck surgery under general anaesthesia: a cross-sectional study.

The Carrico index is the parameter that guides the requirement of oxygen in the postoperative period in patients undergoing head and neck surgery under general anaesthesia: a cross-sectional study.

Background & aims: Altered lung function and consequent decrease in oxygenation has been linked to the duration of anaesthesia. This necessitates oxygen monitoring and supplementation in the perioperative period. But, evidence is lacking regarding the parameter that guides best the oxygen supplementation in the postoperative period and the parameter that correlates best with the duration of anaesthesia.

Methods: Adult patients scheduled for head & neck surgery under general anaesthesia were recruited. Two radial arterial blood samples one at pre-induction and the other at one hour after extubation were obtained. Primary outcome measures were partial pressure of oxygen (PaO2), saturation (SpO2), arterial oxygen content (CaO2) and Carrico index (PaO2/FiO2) and their relation with duration of anaesthesia.

Results: Data from 112 patients showed a hypoxaemia incidence of 11.6%. We observed a drop in the mean CaO2 and haemoglobin concentration but a rise in the mean PaO2 at recovery. The mean PaO2/FiO2 deteriorated by 225.65 ± 72.46 (95% CI 367.66, 83.64, p = 0.000) at recovery and there was a significant correlation (r = 0.2, p = 0.03) between duration of anaesthesia and decrease in PaO2/FiO2 at recovery with a regression coefficient of 0.27 (95% CI 0.02, 0.50).

Conclusions: The Carrico index was proven to be the best parameter which needs to be monitored perioperatively to detect the alteration in the gaseous exchange in patients undergoing general anaesthesia for head and neck surgery. There is a positive correlation between the decrease in the Carrico index and the duration of anaesthesia especially when it is prolonged beyond 150 minutes.

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来源期刊
CiteScore
2.30
自引率
0.00%
发文量
0
期刊介绍: The Romanian Journal of Anaesthesia and Intensive Care is the official journal of the Romanian Society of Anaesthesia and Intensive Care and has been published continuously since 1994. It is intended mainly for anaesthesia and intensive care providers, but it is also aimed at specialists in emergency medical care and in pain research and management. The Journal is indexed in Scopus, Embase, PubMed Central as well as the databases of the Romanian Ministry of Education and Research (CNCSIS) B+ category. The Journal publishes two issues per year, the first one in April and the second one in October, and contains original articles, reviews, case reports, letters to the editor, book reviews and commentaries. The Journal is distributed free of charge to the members of the Romanian Society of Anaesthesia and Intensive Care.
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