蛔虫感染致特应性皮炎1例。

Q2 Medicine
Clinical and Molecular Allergy Pub Date : 2018-04-10 eCollection Date: 2018-01-01 DOI:10.1186/s12948-018-0088-5
Rosanna Qualizza, Laura M Losappio, Fabiana Furci
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引用次数: 5

摘要

背景:寄生虫感染刺激总和特异性IgE的产生,在犬弓形虫感染的情况下,对应于慢性过敏症状。其他感染也可能有类似的症状,如蛔虫感染。类蚓蛔虫是一种大型线虫,可引起腹痛、恶心、呕吐、腹胀、厌食和间歇性腹泻。蛔虫病和高IgE水平的患者也可能出现过敏样症状,如哮喘、荨麻疹和特应性皮炎。病例介绍:我们报告一例由类蛔虫引起的特应性皮炎,这表明寄生虫感染在长期皮炎患者中的重要作用。患者是一名12岁的女性,从婴儿早期就患有特应性皮炎和哮喘。她用口服贝他米松和局部吡美莫司治疗皮炎,收效甚微。经甲苯达唑治疗两个周期后,患者症状渐进式改善。结论:在皮炎患者中,不应排除类蛔虫感染:充分的驱虫药治疗可能导致疾病完全消退。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A case of atopic dermatitis caused by <i>Ascaris lumbricoides</i> infection.

A case of atopic dermatitis caused by Ascaris lumbricoides infection.

Background: Parasite infections stimulate total and specific IgE production that, in the case of Toxocara canis infection, corresponds to chronic allergic symptoms. There may also be other infections which have similar symptoms, such as Ascaris lumbricoides infection. Ascaris lumbricoides is a large nematode that causes abdominal pain, nausea, vomiting, bloating, anorexia and intermittent diarrhoea. Patients with ascaridiasis and high IgE levels may also have allergy-like symptoms such as asthma, urticaria and atopic dermatitis.

Case presentation: We report a case of atopic dermatitis caused by Ascaris lumbricoides which shows the important role of parasitic infection in patients with long-lasting dermatitis. The patient was a 12-year old female suffering since early infancy from atopic dermatitis and asthma. She was treated for dermatitis with oral bethametasone and topical pimecrolimus with little benefit. After two cycles of mebendazole therapy, the patient showed progressive improvement of symptoms.

Conclusions: In patients with dermatitis, Ascaris lumbricoides infection should be not excluded: adequate anthelmintic treatment may result in complete regression from the disease.

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来源期刊
Clinical and Molecular Allergy
Clinical and Molecular Allergy Medicine-Immunology and Allergy
CiteScore
8.20
自引率
0.00%
发文量
11
审稿时长
13 weeks
期刊介绍: Clinical and Molecular Allergy is an open access, peer-reviewed, online journal that publishes research on human allergic and immunodeficient disease (immune deficiency not related to HIV infection/AIDS). The scope of the journal encompasses all aspects of the clinical, genetic, molecular and inflammatory aspects of allergic-respiratory (Type 1 hypersensitivity) and non-AIDS immunodeficiency disorders. However, studies of allergic/hypersensitive aspects of HIV infection/AIDS or drug desensitization protocols in AIDS are acceptable. At the basic science level, this includes original work and reviews on the genetic and molecular mechanisms underlying the inflammatory response.
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