Biktorija Ana Buljević, Matias Trbušić, Diana Delić-Brkljačić, Ivan Malčić
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[MYOCARDIAL INFARCTION AS A CONSEQUENCE OF CHILDHOOD POLYARTERITIS NODOSA – CASE REPORT].
Polyarteritis nodosa (PAN) is a systemic vasculitis histologically characterized by necrotic lesions of small and medium-
sized arteries occurring mostly in their bifurcations. PAN is a multi-organ disorder that affects numerous visceral
arteries and leads to inflammation and necrosis, which may result in ischemia of vital organs. The etiology of the disease
is unknown. It occurs in four forms - cutaneous (most common), classic, systemic, and microscopic. PAN preferably
affects the renal and coronary arteries. The most common findings in the affected blood vessels are aneurysm, thrombosis,
and stenosis. Cardiac complications are rare in children, but 35% of patients develop a complication in adulthood. The
most common complication in adulthood is cardiac decompensation, which can be explained as a consequence of longstanding
hypertension and changes in coronary blood vessels. The incidence of myocardial infarction is low, particularly
in young patients. This paper describes a 25-year-old patient with acute myocardial infarction accompanied by changes
in the coronary blood vessels and persistent arterial hypertension as a result of PAN diagnosed in childhood.