儿童结节性多动脉炎所致心肌梗死1例报告。

Reumatizam Pub Date : 2016-01-01
Biktorija Ana Buljević, Matias Trbušić, Diana Delić-Brkljačić, Ivan Malčić
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引用次数: 0

摘要

结节性多动脉炎(PAN)是一种系统性血管炎,其组织学特征为中小型动脉的坏死病变,主要发生在其分叉处。PAN是一种多脏器疾病,可累及众多脏器动脉,引起炎症和坏死,可导致重要脏器缺血。这种疾病的病因尚不清楚。它发生在四种形式-皮肤(最常见),经典,全身和显微镜。PAN主要影响肾动脉和冠状动脉。在受影响的血管中最常见的发现是动脉瘤,血栓形成和狭窄。心脏并发症在儿童中很少见,但35%的患者在成年后出现并发症。成年期最常见的并发症是心脏失代偿,这可以解释为长期高血压和冠状血管改变的结果。心肌梗死的发生率较低,特别是在年轻患者中。本文报告了一位25岁的急性心肌梗死患者,其冠状动脉血管改变和持续的动脉高血压是儿童时期诊断为PAN的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[MYOCARDIAL INFARCTION AS A CONSEQUENCE OF CHILDHOOD POLYARTERITIS NODOSA – CASE REPORT].

Polyarteritis nodosa (PAN) is a systemic vasculitis histologically characterized by necrotic lesions of small and medium- sized arteries occurring mostly in their bifurcations. PAN is a multi-organ disorder that affects numerous visceral arteries and leads to inflammation and necrosis, which may result in ischemia of vital organs. The etiology of the disease is unknown. It occurs in four forms - cutaneous (most common), classic, systemic, and microscopic. PAN preferably affects the renal and coronary arteries. The most common findings in the affected blood vessels are aneurysm, thrombosis, and stenosis. Cardiac complications are rare in children, but 35% of patients develop a complication in adulthood. The most common complication in adulthood is cardiac decompensation, which can be explained as a consequence of longstanding hypertension and changes in coronary blood vessels. The incidence of myocardial infarction is low, particularly in young patients. This paper describes a 25-year-old patient with acute myocardial infarction accompanied by changes in the coronary blood vessels and persistent arterial hypertension as a result of PAN diagnosed in childhood.

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