改性生物活性玻璃对牙本质再矿化和阻塞牙本质小管的功效

Mahshid Saffarpour, Maryam Mohammadi, Mohammadreza Tahriri, Azadeh Zakerzadeh
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引用次数: 0

摘要

研究目的本研究评估了改性生物活性玻璃(MBG)对牙本质再矿化和阻塞牙本质小管的功效:从 20 颗第三磨牙上制作了 36 个牙本质盘,并在 12% 的乳酸溶液中保存两周以诱导脱矿化。样本分为三组(n=12):使用 BG 后,样品在人工唾液中分别保存 7、14 和 21 天。使用衰减全反射-傅立叶变换红外光谱(ATR-FTIR)、X 射线衍射(XRD)分析、扫描电子显微镜(SEM)和能量色散 X 射线(EDX)分析来评估再矿化情况。此外,还将 6 个牙本质圆盘分为三组,即 BG、用 5% Sr 修饰的 BG 和用 10% Sr 修饰的 BG,以检查管状咬合。牙盘用 0.5M EDTA 蚀刻两分钟,然后在人工唾液中保存 7 天。在扫描电镜下评估牙本质表面形态的变化:第 3 组在第 7 天和第 14 天显示出较高的再矿化率,但第 21 天时再矿化率有所下降。第 2 组在第 7、14 和 21 天的再矿化率较高。牙本质小管被 BG 和用 5%锶修饰的 BG 部分阻塞,而使用用 10%锶修饰的 BG 后,牙本质小管几乎完全阻塞:结论:锶能增加再矿化。在 BG 中添加 10%的锶可促进磷灰石的形成,但磷灰石会随着时间的推移而溶解。在 BG 中添加 5%的锶可稳定磷灰石晶格并增加再矿化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Efficacy of Modified Bioactive Glass for Dentin Remineralization and Obstruction of Dentinal Tubules.

Efficacy of Modified Bioactive Glass for Dentin Remineralization and Obstruction of Dentinal Tubules.

Efficacy of Modified Bioactive Glass for Dentin Remineralization and Obstruction of Dentinal Tubules.

Efficacy of Modified Bioactive Glass for Dentin Remineralization and Obstruction of Dentinal Tubules.

Objectives: This study assessed the efficacy of modified bioactive glass (MBG) for dentin remineralization and obstruction of dentinal tubules.

Materials and methods: Thirty-six dentin discs were made from 20 third molars and were stored in 12% lactic acid solution for two weeks to induce demineralization. The samples were divided into three groups (n=12): 1- BG, 2- BG modified with 5% strontium (Sr) and 3- BG modified with 10% Sr. After applying the BG, the samples were stored in artificial saliva for 7, 14 and 21 days. Attenuated Total Reflection-Fourier Transform Infrared Spectroscopy (ATR-FTIR), X-ray Diffraction (XRD) analysis, Scanning Electron Microscopy (SEM), and Energy-Dispersive X-ray (EDX) analysis were used to assess remineralization. Also, 6 dentin discs were divided into three groups of BG, BG modified with 5% Sr and BG modified with 10% Sr, to examine tubular occlusion. The discs were etched using 0.5M of EDTA for two minutes and were stored in artificial saliva for 7 days. Changes in dentin surface morphology were evaluated under SEM.

Results: Group 3 showed high rates of remineralization at days 7 and 14, although the rate decreased at day 21. Group 2 exhibited high rates of remineralization at days 7, 14 and 21. Dentinal tubules were partially occluded by BG and BG modified with 5% Sr, while they were almost completely obstructed after the use of BG modified with 10% Sr.

Conclusions: Strontium increases remineralization. Addition of 10% Sr to BG enhances apatite formation; however, the apatite dissolves over time. Addition of 5% Sr to BG stabilizes the apatite lattice and increases the remineralization.

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