Sriram Gubbi, Nir Barzilai, Jill Crandall, Joe Verghese, Sofiya Milman
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However, the contribution of dietary habits to protection from disease has not been systematically assessed in families with exceptional longevity.</p><p><strong>Objective: </strong>The aim of this study is to compare dietary patterns between individuals with parental longevity and individals without parental longevity.</p><p><strong>Methods: </strong>Dietary intake was evaluated using the Block Brief Food Frequency Questionnaire in 234 community dwelling Ashkenazi Jewish adults aged 65 years and older who were participants of the LonGenity study, which enrolls the offspring of parents with exceptional longevity (OPEL) and offspring of parents with usual survival (OPUS).</p><p><strong>Results: </strong>OPEL constituted 38% of the subjects. The two groups had similar daily intake of total calories (1119 vs. 1218 kcal, <i>p</i> = 0.83), grams of cholesterol (141 g vs. 143 g, <i>p</i> = 0.19), and grams of sodium (1324 g vs.1475 g, <i>p</i> = 0.45), in OPEL vs. OPUS respectively. 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引用次数: 0
摘要
背景：与非长寿家庭相比，超常长寿者及其后代的老年相关疾病发病率较低。然而，饮食习惯对长寿家庭预防疾病的贡献尚未得到系统评估：本研究旨在比较父母长寿的个体与父母不长寿的个体之间的饮食模式：方法：使用 Block 简要食物频率问卷对 234 名居住在社区的 65 岁及以上阿什肯纳兹犹太裔成年人的饮食摄入情况进行评估，这些人都是长寿研究的参与者，该研究招募了父母长寿者的后代（OPEL）和父母正常生存者的后代（OPUS）：结果：OPEL 占研究对象的 38%。两组受试者每天摄入的总热量（1119 千卡对 1218 千卡，P = 0.83）、胆固醇克数（141 克对 143 克，P = 0.19）和钠克数（1324 克对 1475 克，P = 0.45）分别与 OPEL 和 OPUS 相似。在对年龄和性别进行调整后，OPEL 和 OPUS 在其他宏量营养素、微量营养素、营养补充剂的摄入量以及各类食物的摄入量方面也没有明显差异：讨论：健康的饮食与降低罹患多种慢性疾病的风险有关。我们的研究表明，OPEL 和 OPUS 之间的饮食摄入量并无差异；因此，这表明长寿基因在保护家族长寿者免受疾病侵袭方面发挥了作用：结论：与没有长寿父母的个体相比，长寿父母的后代在饮食模式上没有差异。
The role of dietary patterns and exceptional parental longevity in healthy aging.
Background: Individuals with exceptional longevity and their offspring manifest a lower prevalence of age-related diseases than families without longevity. However, the contribution of dietary habits to protection from disease has not been systematically assessed in families with exceptional longevity.
Objective: The aim of this study is to compare dietary patterns between individuals with parental longevity and individals without parental longevity.
Methods: Dietary intake was evaluated using the Block Brief Food Frequency Questionnaire in 234 community dwelling Ashkenazi Jewish adults aged 65 years and older who were participants of the LonGenity study, which enrolls the offspring of parents with exceptional longevity (OPEL) and offspring of parents with usual survival (OPUS).
Results: OPEL constituted 38% of the subjects. The two groups had similar daily intake of total calories (1119 vs. 1218 kcal, p = 0.83), grams of cholesterol (141 g vs. 143 g, p = 0.19), and grams of sodium (1324 g vs.1475 g, p = 0.45), in OPEL vs. OPUS respectively. There were also no significant differences in the intake of other macronutrients, micronutrients, nutritional supplements and consumption of various food groups between OPEL and OPUS after adjustment for age and sex.
Discussion: A healthy diet is associated with a lower risk of several chronic diseases. Our study revealed that dietary intake did not differ between OPEL and OPUS; thus, pointing to the role of longevity genes in protecting from disease among individuals with familial longevity.
Conclusion: The offspring of long-lived parents do not differ in their dietary patterns compared to individuals without parental longevity.
期刊介绍：
Nutrition and Healthy Aging is an international forum for research on nutrition as a means of promoting healthy aging. It is particularly concerned with the impact of nutritional interventions on the metabolic and molecular mechanisms which modulate aging and age-associated diseases, including both biological responses on the part of the organism itself and its micro biome. Results emanating from both model organisms and clinical trials will be considered. With regards to the latter, the journal will be rigorous in only accepting for publication well controlled, randomized human intervention trials that conform broadly with the current EFSA and US FDA guidelines for nutritional clinical studies. The journal will publish research articles, short communications, critical reviews and conference summaries, whilst open peer commentaries will be welcomed.
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