孤立社区的生殖道感染:Príncipe岛上的100名妇女。

Q2 Medicine

Infectious Diseases in Obstetrics and Gynecology Pub Date : 2017-01-01 Epub Date: 2017-11-13 DOI:10.1155/2017/3058569

Pedro Vieira-Baptista, Svitrigaile Grinceviciene, Gert Bellen, Carlos Sousa, Conceição Saldanha, Davy Vanden Broeck, John-Paul Bogers, Gilbert Donders

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引用次数: 9

摘要

目的:了解Príncipe ( o tom和Príncipe)妇女阴道微生物群及性传播感染(STIs)发生率。方法:对连续100名妇女进行横断面研究，邀请她们进行免费预约和宫颈癌筛查。获得阴道切片(湿片显微镜)和宫颈样本(ThinPrep®)(巴氏涂片、高危人乳头瘤病毒[HR-HPV]、淋病奈瑟菌[NG]、阴道绦虫[TV]和沙眼衣原体[CT])。结果:TV、NG、CT和HIV的检出率分别为8.0%、2.0%、3.0%和2.0%，以年轻女性多见。HR-HPV阳性率为36.7%;2例HPV18阳性，无HPV16阳性。HPV与其他性传播感染的合并感染率为8.3%。阴道菌群异常(AVF)患病率为82.5%，细菌性阴道病(BV)患病率为54.6%，中度/重度需氧性阴道炎(msAV)患病率为25.8%。HR-HPV与BV无相关性(p = 0.67)。巴氏试验异常与msAV的相关性无统计学意义(p = 0.08)。结论:NG、CT、TV、HR-HPV患病率与预期相符，HR-AVF患病率较高。HPV16和HPV18的低流行率在设计预防和接种计划时必须考虑到;该设置可作为疫苗接种后情景的模型。

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Genital Tract Infections in an Isolated Community: 100 Women of the Príncipe Island.

Objective: To characterize the vaginal microbiome and the rate of sexually transmitted infections (STIs) in the women of Príncipe (São Tomé and Príncipe).

Methods: Cross-sectional study of 100 consecutive women, invited for a free appointment and cervical cancer screening. A vaginal slide (wet mount microscopy) and a cervical sample (ThinPrep®) (Pap test, high risk human papillomavirus [HR-HPV], N. gonorrhea [NG], T. vaginalis [TV], and C. trachomatis [CT]) were obtained.

Results: TV, NG, CT, and HIV were found in 8.0%, 2.0%, 3.0%, and 2.0%, respectively, and were more prevalent in younger women. HR-HPV was positive in 36.7%; 2 were positive for HPV18, but none for HPV16. Coinfection of HPV with other STIs was 8.3%. Prevalence of abnormal vaginal flora (AVF) was 82.5%, mostly bacterial vaginosis (BV) 54.6%, and moderate/severe aerobic vaginitis (msAV) 25.8%. HR-HPV was not related to BV (p = 0.67). The association of abnormal Pap test with msAV was not significant (p = 0.08).

Conclusion: The prevalence of NG, CT, TV, and HR-HPV was according to expected, while that of HR-AVF was higher. The surprisingly low prevalence of HPV16 and HPV18 must be considered in the design of programs for prevention and vaccination; this setting can be useful as a model for postvaccination scenarios.

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来源期刊

Infectious Diseases in Obstetrics and Gynecology Medicine-Obstetrics and Gynecology

CiteScore

3.80

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： Infectious Diseases in Obstetrics and Gynecology aims to disseminate new and important information to clinicians and other health care providers, scientists, and researchers involved in the study or treatment of infectious diseases, especially those affecting the female patient. Its ultimate aim is to advance knowledge and encourage research, thereby improving the prevention or diagnosis and treatment of patients affected by such diseases.