由药物制剂诱导的细胞遗传学重述,是器官移植中紧急保护形成的普遍阶段。

N A Onishchenko
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引用次数: 0

摘要

在这篇文章中,现代代表的细胞机制形成的药物制剂的紧急保护器官免受损害的移植给出。在肾脏缺血性损伤的一个例子中,它显示,在使用不同药理学组的制剂时,在细胞系统的非特异性适应综合征的范围内,这些药理学组中最表达的保护作用,明显地在器官中诱导了细胞遗传学再现的进化发展迹象:以激活糖酵解和大分子构象重组为代价,在较低水平上支持细胞内稳态,也改变细胞内的水含量-减少自由和增加结合。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cytogenetic recapitulation, induced by medical preparations, as the universal stage of formation of urgent protection against damage at organ transplantation.

In this article modern representations about cellular mechanisms of formation by pharmacological preparations of urgent protection of organs against damage are given at transplantation. On an example of ischemic damage of kidneys it is shown, that at use of preparations of different pharmacological groups by the most expressed protective effect those from them which operating within the limits of a nonspecific adaptive syndrome of cellular systems, clearly induce in organs the evolutional developed signs of cytogenetic recapitulation possess: support a cellular homeostasis at the lowered level at the expense of activation of a glycolysis and conformational reorganizations of macromolecules, and also change in cells of water contain- decrease of free and increase of bound.

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