基因组数据融入医疗从业者的日常工作-决策的数字工具。

Sakari Jokiranta, Kristina Hotakainen, Iiris Salonen, Pasi Pöllänen, Kai-Petri Hänninen, Jari Forsström, Ilkka Kunnamo
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引用次数: 0

摘要

最近的技术发展使几个基因变异或序列甚至整个基因组的快速和经济有效的同时分析成为可能。尽管基因组信息可能在临床上有新的应用,例如发现受多达50,000个可变DNA区域影响的疾病的个体风险,或在开药前检测药物遗传风险,但这给医疗从业者带来了挑战。新的数字工具为利用基因组数据铺平了道路,为医生和患者提供了方便的访问和清晰的临床解释。在这篇综述中,我们描述了一些这些工具及其临床应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Genomic data into everyday work of a medical practitioner - digital tools for decision-making.

Recent technological development has enabled fast and cost-effective simultaneous analyses of several gene variants or sequence of even the whole genome. For medical practitioners this has created challenges although genomic information may be clinically useful in new applications such as finding out individual risk for diseases influenced by as many as 50,000 variable DNA regions or in detecting pharmacogenetic risks prior to prescribing a medicine. New digital tools have paved the way for utilization of genomic data via easy access and clear clinical interpretation for both doctor and patient. In this review we describe some of these tools and applications for clinical use.

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