Juan Nieves-Rivera, Crystal Sulia, Rosbel Gonzalez, Luz Figueroa, Héctor Banchs, Pablo Altieri, Wilma González
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Psoriasis and Coronary Artery Disease in Hispanics.
Psoriasis is an immune disorder characterized by chronic activation of systemic
inflammation. Morbidity and mortality in patients with psoriasis is attributed
mainly to cardiovascular disease. There are studies in Caucasians and African-
Americans, but little is known about how psoriasis is associated to coronary
artery disease (CAD) in Hispanics. We intend to describe the angiographic findings
of a group of Puerto Rican patients with psoriasis. Retrospective cohort study
of 46 patients with psoriasis were studied. Coronary angiographic reports were
reviewed, and collected data was statistically analized. Population median age
was 56, and 72% were males. Of the 46 patients, 27 had CAD by angiographic
criteria (58.7%). Twelve patients were referred to bypass graft surgery, 8 underwent
coronary stent placement, and 7 were treated medically. Whether psoriasis
can be considered a risk factor for developing CAD is still on debate. More
than 50% of our patients with psoriasis had angiographic evidence of CAD. Adjusting
for traditional cardiovascular risk factors, we found no significant association
(p>0.05) with CAD. We believe that inflammation plays a contributing role
in the increased risk of CAD in these patients. The importance of this study relies
on being the first retrospective analysis in a group of Hispanics trying to determine
an association between coronary artery disease and psoriasis when in Puerto
Rico, coronary artery disease is 30% less than in the United States.