转换,人为障碍和装病:一个独特的模式或连续?

Q3 Medicine
Frontiers of Neurology and Neuroscience Pub Date : 2018-01-01 Epub Date: 2017-11-17 DOI:10.1159/000475699
Silvio Galli, Laurent Tatu, Julien Bogousslavsky, Selma Aybek
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引用次数: 31

摘要

本章的目的是强调最近的发现有关生理病理,诊断和管理的转换,人为障碍,和装病。转换障碍是无意中产生的神经症状,而装病和人为障碍则是在内部或外部激励下自愿产生的症状。他们有密切的历史,这经常被混淆。从业人员经常面临医学上无法解释的症状;他们几乎占了神经科医生咨询的30%。第一个挑战是发现它们,最近的研究已经证实了基于不连贯和不一致的“积极”临床床边症状的重要性,例如胡佛症状对转换障碍的诊断。功能神经影像学使我们对其病理生理学有了更好的了解,并强调了与假想症不同的、与运动、情绪和边缘网络相关的转换障碍的异常大脑激活模式。这支持了Charcot提出的“精神动力损伤”理论,这也反映在DSM-5中引入的新术语:功能性神经障碍。多学科治疗推荐行为认知疗法,抗抑郁药治疗常见的共病焦虑或抑郁,以及物理治疗。应将人为障碍和装病与转换障碍明确区分开来。当装病是医学法律案件中遇到的非医学状况时,应将人为障碍视为一种精神疾病,需要对其生理病理和治疗进行更多的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Conversion, Factitious Disorder and Malingering: A Distinct Pattern or a Continuum?

This chapter is aimed at highlighting the recent findings concerning physiopathology, diagnosis, and management of conversion, factitious disorder, and malingering. Conversion disorder is the unintentional production of neurological symptom, whereas malingering and factitious disorder represent the voluntary production of symptoms with internal or external incentives. They have a close history and this has been frequently confounded. Practitioners are often confronted to medically unexplained symptoms; they represent almost 30% of neurologist's consultation. The first challenge is to detect them, and recent studies have confirmed the importance of "positive" clinical bedside signs based on incoherence and discordance, such as the Hoover's sign for the diagnosis of conversion disorder. Functional neuroimaging has allowed a better understanding of the pathophysiology, and highlighted abnormal cerebral activation patterns in conversion disorder in relation to motor, emotional, and limbic networks, different from feigners. This supports the theory evoked by Charcot of a "psychodynamic lesion," which is also reflected by the new term introduced in the DSM-5: functional neurological disorder. Multidisciplinary therapy is recommended with behavioral cognitive therapy, antidepressant to treat frequent comorbid anxiety or depression, and physiotherapy. Factitious disorder and malingering should be clearly delineated from conversion disorder. Factitious disorder should be considered as a mental illness and more research on its physiopathology and treatment is needed, when malingering is a non-medical condition encountered in medico-legal cases.

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来源期刊
Frontiers of Neurology and Neuroscience
Frontiers of Neurology and Neuroscience Medicine-Neurology (clinical)
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期刊介绍: Focusing on topics in the fields of both Neurosciences and Neurology, this series provides current and unique information in basic and clinical advances on the nervous system and its disorders.
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