{"title":"静脉注射氨甲环酸能减少手术辅助下快速腭扩张时的失血吗?","authors":"Emine Akbas, Zerrin Cebi, Erol Cansiz, Sabri Cemil Isler, Sırmahan Cakarer","doi":"10.17096/jiufd.94203","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to evaluate the efficacy of tranexamic acid (TXA) in reducing blood loss during surgically assisted rapid palatal expansion (SARPE) procedure.</p><p><strong>Subjects and methods: </strong>A total of 34 patients (12 male, 22 female) who had been treated surgically under general anesthesia with SARPE including pterygoid disjunction for transverse maxillary deficiency (TMD) were included in this study. The study group (n=17) received intravenous (IV) TXA 10 mg/kg as a preoperative bolus; the control group (n=17) received normal saline solution. Preoperative and postoperative haemoglobin and haematocrit values, intraoperative blood loss, and any blood product transfusion were recorded.</p><p><strong>Results: </strong>Blood loss during SARPE was statistically significantly less in the study group than the control group (p=0.0001).</p><p><strong>Conclusion: </strong>Preoperative IV administration of TXA can effectively control blood loss during when SARPE with pterygoid disjunction is performed.</p>","PeriodicalId":30947,"journal":{"name":"Journal of Istanbul University Faculty of Dentistry","volume":"51 3","pages":"32-37"},"PeriodicalIF":0.0000,"publicationDate":"2017-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/74/09/jiufd-051-032.PMC5624143.pdf","citationCount":"2","resultStr":"{\"title\":\"Does intravenous tranexamic acid reduce blood loss during surgically assisted rapid palatal expansion?\",\"authors\":\"Emine Akbas, Zerrin Cebi, Erol Cansiz, Sabri Cemil Isler, Sırmahan Cakarer\",\"doi\":\"10.17096/jiufd.94203\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>The purpose of this study was to evaluate the efficacy of tranexamic acid (TXA) in reducing blood loss during surgically assisted rapid palatal expansion (SARPE) procedure.</p><p><strong>Subjects and methods: </strong>A total of 34 patients (12 male, 22 female) who had been treated surgically under general anesthesia with SARPE including pterygoid disjunction for transverse maxillary deficiency (TMD) were included in this study. The study group (n=17) received intravenous (IV) TXA 10 mg/kg as a preoperative bolus; the control group (n=17) received normal saline solution. Preoperative and postoperative haemoglobin and haematocrit values, intraoperative blood loss, and any blood product transfusion were recorded.</p><p><strong>Results: </strong>Blood loss during SARPE was statistically significantly less in the study group than the control group (p=0.0001).</p><p><strong>Conclusion: </strong>Preoperative IV administration of TXA can effectively control blood loss during when SARPE with pterygoid disjunction is performed.</p>\",\"PeriodicalId\":30947,\"journal\":{\"name\":\"Journal of Istanbul University Faculty of Dentistry\",\"volume\":\"51 3\",\"pages\":\"32-37\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-10-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/74/09/jiufd-051-032.PMC5624143.pdf\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Istanbul University Faculty of Dentistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17096/jiufd.94203\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2017/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Istanbul University Faculty of Dentistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17096/jiufd.94203","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2017/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Does intravenous tranexamic acid reduce blood loss during surgically assisted rapid palatal expansion?
Purpose: The purpose of this study was to evaluate the efficacy of tranexamic acid (TXA) in reducing blood loss during surgically assisted rapid palatal expansion (SARPE) procedure.
Subjects and methods: A total of 34 patients (12 male, 22 female) who had been treated surgically under general anesthesia with SARPE including pterygoid disjunction for transverse maxillary deficiency (TMD) were included in this study. The study group (n=17) received intravenous (IV) TXA 10 mg/kg as a preoperative bolus; the control group (n=17) received normal saline solution. Preoperative and postoperative haemoglobin and haematocrit values, intraoperative blood loss, and any blood product transfusion were recorded.
Results: Blood loss during SARPE was statistically significantly less in the study group than the control group (p=0.0001).
Conclusion: Preoperative IV administration of TXA can effectively control blood loss during when SARPE with pterygoid disjunction is performed.
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