[瞬时弹性成像——肝脏病变诊断的未来或仅仅是一种尝试]。

Q4 Medicine
Acta Medica Croatica Pub Date : 2015-11-01
T Zavidić, Đ Lovrinić
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引用次数: 0

摘要

每个全科医生为病人提供的综合护理包括熟悉不同的诊断方法。在今天的诊断中,经常有各种肝脏疤痕的迹象,首先需要正确诊断,然后治疗和监测一段时间。慢性肝病是发达国家十大死亡原因之一,也是世界上主要的公共卫生问题之一。在克罗地亚,纤维化和肝硬化在2013年死亡原因中排名第10位,占所有死亡人数的1.95%,在男性中甚至占3.11%。肝纤维化程度是判断肝瘢痕严重程度最直接、最好的指标,而预后取决于肝纤维化的进展。本文就瞬态弹性成像(TE)的基本特性、优缺点、诊断精度及其在医疗实践中的应用作一综述。目前,TE可作为消除肝硬化的诊断方法,并可帮助确定酒精性肝病患者的严重纤维化。通过使用两种非侵入性诊断方法,可以高精度地评估纤维化阶段(F≥2),并避免多达四分之三的活检程序。然而,在将TE纳入诊断算法之前,需要定义肝脏瘢痕形成不同阶段的标准化截断值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[TRANSIENT ELASTOGRAPHY – FUTURE OF DIAGNOSIS OF LIVER LESIONS OR JUST AN ATTEMPT].

Comprehensive care that each general practitioner offers to his patients includes familiarity with different methods of diagnosis. In diagnosis today there are frequent indications of various liver scarring which first need to be diagnosed correctly and then treated and monitored over time. Chronic liver diseases are among the top ten causes of death in developed countries and one of the leading public health issues in the world. In Croatia, fibrosis and cirrhosis ranked 10th among causes of death in 2013, accounting for 1.95% of all deaths and even 3.11% in men. The degree of liver fibrosis is the most direct and the best way to indicate the seriousness of liver scarring, while prognosis depends on advancement of fibrosis. In this paper, we attempted to explain a noninvasive method called transient elastography (TE), its basic properties, advantages and disadvantages, diagnostic precision, as well as its application in medical practice. Currently, TE may be used as a diagnostic method for elimination of cirrhosis and may help determine severe fibrosis in patients with alcohol liver disease. By using two noninvasive diagnostic methods, it is possible to assess the stage of fibrosis (F ≥2) with high accuracy and avoid up to three-fourths of biopsy procedures. However, before including TE in the algorithm of diagnosis, it is necessary to define the standardized cut off values for different stages of liver scarring.

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来源期刊
Acta Medica Croatica
Acta Medica Croatica Medicine-Medicine (all)
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期刊介绍: ACTA MEDICA CROATICA publishes original contributions to medical sciences, that have not been previously published. All manuscripts should be written in English.
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