Hirendra Banerjee, Jamel Joyner, Monet Stevenson, William Kaha, Christopher Krauss, Sasha Hodges, Eduardo Santos, Myla Worthington, Jeffferey Rousch, Gloria Payne, Vinod Manglik, Narendra Banerjee, Brianna Morris, Dayton Bell, Santosh Mandal
{"title":"短通信:研究智能闪光金纳米颗粒在研究前列腺癌细胞系微RNA和癌基因差异表达中的作用。","authors":"Hirendra Banerjee, Jamel Joyner, Monet Stevenson, William Kaha, Christopher Krauss, Sasha Hodges, Eduardo Santos, Myla Worthington, Jeffferey Rousch, Gloria Payne, Vinod Manglik, Narendra Banerjee, Brianna Morris, Dayton Bell, Santosh Mandal","doi":"10.6000/1929-2279.2017.06.02.1","DOIUrl":null,"url":null,"abstract":"<p><p>Nano technology is a cutting edge science which is now effectively used in the field of cancer biology. Smart Flare gold nanoparticles are now used often for differential gene expression analysis. In this manuscript we are reporting the use of micro RNA miR 146a and onco gene EZH2 Smart Flare probes to study their expression in different prostate cancer cell lines and the effect of novel Rhenium compounds on these genes using a flow cytometer and a Fluorescence microscope. Our results showed this novel nanotechnology can be effectively used in cancer biology to successfully detect the effect of novel drugs on oncogenes and could be a very useful tool for next generation of cancer researchers.</p>","PeriodicalId":89799,"journal":{"name":"Journal of cancer research updates","volume":"6 2","pages":"25-28"},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.6000/1929-2279.2017.06.02.1","citationCount":"2","resultStr":"{\"title\":\"Short Communication: Studying the Role of Smart Flare Gold Nano Particles in Studying Micro RNA and Oncogene Differential Expression in Prostate Cancer Cell Lines.\",\"authors\":\"Hirendra Banerjee, Jamel Joyner, Monet Stevenson, William Kaha, Christopher Krauss, Sasha Hodges, Eduardo Santos, Myla Worthington, Jeffferey Rousch, Gloria Payne, Vinod Manglik, Narendra Banerjee, Brianna Morris, Dayton Bell, Santosh Mandal\",\"doi\":\"10.6000/1929-2279.2017.06.02.1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Nano technology is a cutting edge science which is now effectively used in the field of cancer biology. Smart Flare gold nanoparticles are now used often for differential gene expression analysis. In this manuscript we are reporting the use of micro RNA miR 146a and onco gene EZH2 Smart Flare probes to study their expression in different prostate cancer cell lines and the effect of novel Rhenium compounds on these genes using a flow cytometer and a Fluorescence microscope. Our results showed this novel nanotechnology can be effectively used in cancer biology to successfully detect the effect of novel drugs on oncogenes and could be a very useful tool for next generation of cancer researchers.</p>\",\"PeriodicalId\":89799,\"journal\":{\"name\":\"Journal of cancer research updates\",\"volume\":\"6 2\",\"pages\":\"25-28\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.6000/1929-2279.2017.06.02.1\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of cancer research updates\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.6000/1929-2279.2017.06.02.1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2017/6/14 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of cancer research updates","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6000/1929-2279.2017.06.02.1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2017/6/14 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
摘要
纳米技术是一门前沿科学，目前已被有效地应用于癌症生物学领域。Smart Flare金纳米颗粒现在经常用于差异基因表达分析。在这篇论文中，我们报告了使用微RNA miR 146a和癌基因EZH2 Smart Flare探针在不同前列腺癌细胞系中研究它们的表达，以及使用流式细胞仪和荧光显微镜研究新型铼化合物对这些基因的影响。我们的研究结果表明，这种新颖的纳米技术可以有效地用于癌症生物学，成功地检测新药对致癌基因的影响，并可能成为下一代癌症研究人员非常有用的工具。
Short Communication: Studying the Role of Smart Flare Gold Nano Particles in Studying Micro RNA and Oncogene Differential Expression in Prostate Cancer Cell Lines.
Nano technology is a cutting edge science which is now effectively used in the field of cancer biology. Smart Flare gold nanoparticles are now used often for differential gene expression analysis. In this manuscript we are reporting the use of micro RNA miR 146a and onco gene EZH2 Smart Flare probes to study their expression in different prostate cancer cell lines and the effect of novel Rhenium compounds on these genes using a flow cytometer and a Fluorescence microscope. Our results showed this novel nanotechnology can be effectively used in cancer biology to successfully detect the effect of novel drugs on oncogenes and could be a very useful tool for next generation of cancer researchers.
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