体素模型的自动修改和融合以构建具有异质乳腺组织的体模:在MRI模拟中的应用。

Journal of biomedical graphics and computing Pub Date : 2017-01-01 Epub Date: 2017-02-26 DOI:10.5430/jbgc.v7n1p1
Joseph V Rispoli, Steven M Wright, Craig R Malloy, Mary P McDougall
{"title":"体素模型的自动修改和融合以构建具有异质乳腺组织的体模:在MRI模拟中的应用。","authors":"Joseph V Rispoli,&nbsp;Steven M Wright,&nbsp;Craig R Malloy,&nbsp;Mary P McDougall","doi":"10.5430/jbgc.v7n1p1","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Human voxel models incorporating detailed anatomical features are vital tools for the computational evaluation of electromagnetic (EM) fields within the body. Besides whole-body human voxel models, phantoms representing smaller heterogeneous anatomical features are often employed; for example, localized breast voxel models incorporating fatty and fibroglandular tissues have been developed for a variety of EM applications including mammography simulation and dosimetry, magnetic resonance imaging (MRI), and ultra-wideband microwave imaging. However, considering wavelength effects, electromagnetic modeling of the breast at sub-microwave frequencies necessitates detailed breast phantoms in conjunction with whole-body voxel models.</p><p><strong>Methods: </strong>Heterogeneous breast phantoms are sized to fit within radiofrequency coil hardware, modified by voxel-wise extrusion, and fused to whole-body models using voxel-wise, tissue-dependent logical operators. To illustrate the utility of this method, finite-difference time-domain simulations are performed using a whole-body model integrated with a variety of available breast phantoms spanning the standard four tissue density classifications representing the majority of the population.</p><p><strong>Results: </strong>The software library uses a combination of voxel operations to seamlessly size, modify, and fuse eleven breast phantoms to whole-body voxel models. The software is publicly available on GitHub and is linked to the file exchange at MATLAB<sup>®</sup> Central. Simulations confirm the proportions of fatty and fibroglandular tissues in breast phantoms have significant yet predictable implications on projected power deposition in tissue.</p><p><strong>Conclusions: </strong>Breast phantoms may be modified and fused to whole-body voxel models using the software presented in this work; user considerations for the open-source software and resultant phantoms are discussed. Furthermore, results indicate simulating breast models as predominantly fatty tissue can considerably underestimate the potential for tissue heating in women with substantial fibroglandular tissue.</p>","PeriodicalId":89580,"journal":{"name":"Journal of biomedical graphics and computing","volume":"7 1","pages":"1-7"},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/jbgc.v7n1p1","citationCount":"7","resultStr":"{\"title\":\"Automated modification and fusion of voxel models to construct body phantoms with heterogeneous breast tissue: Application to MRI simulations.\",\"authors\":\"Joseph V Rispoli,&nbsp;Steven M Wright,&nbsp;Craig R Malloy,&nbsp;Mary P McDougall\",\"doi\":\"10.5430/jbgc.v7n1p1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Human voxel models incorporating detailed anatomical features are vital tools for the computational evaluation of electromagnetic (EM) fields within the body. Besides whole-body human voxel models, phantoms representing smaller heterogeneous anatomical features are often employed; for example, localized breast voxel models incorporating fatty and fibroglandular tissues have been developed for a variety of EM applications including mammography simulation and dosimetry, magnetic resonance imaging (MRI), and ultra-wideband microwave imaging. However, considering wavelength effects, electromagnetic modeling of the breast at sub-microwave frequencies necessitates detailed breast phantoms in conjunction with whole-body voxel models.</p><p><strong>Methods: </strong>Heterogeneous breast phantoms are sized to fit within radiofrequency coil hardware, modified by voxel-wise extrusion, and fused to whole-body models using voxel-wise, tissue-dependent logical operators. To illustrate the utility of this method, finite-difference time-domain simulations are performed using a whole-body model integrated with a variety of available breast phantoms spanning the standard four tissue density classifications representing the majority of the population.</p><p><strong>Results: </strong>The software library uses a combination of voxel operations to seamlessly size, modify, and fuse eleven breast phantoms to whole-body voxel models. The software is publicly available on GitHub and is linked to the file exchange at MATLAB<sup>®</sup> Central. Simulations confirm the proportions of fatty and fibroglandular tissues in breast phantoms have significant yet predictable implications on projected power deposition in tissue.</p><p><strong>Conclusions: </strong>Breast phantoms may be modified and fused to whole-body voxel models using the software presented in this work; user considerations for the open-source software and resultant phantoms are discussed. Furthermore, results indicate simulating breast models as predominantly fatty tissue can considerably underestimate the potential for tissue heating in women with substantial fibroglandular tissue.</p>\",\"PeriodicalId\":89580,\"journal\":{\"name\":\"Journal of biomedical graphics and computing\",\"volume\":\"7 1\",\"pages\":\"1-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.5430/jbgc.v7n1p1\",\"citationCount\":\"7\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of biomedical graphics and computing\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5430/jbgc.v7n1p1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2017/2/26 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biomedical graphics and computing","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5430/jbgc.v7n1p1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2017/2/26 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7

摘要

背景:包含详细解剖特征的人体体素模型是计算评估体内电磁场(EM)的重要工具。除了全身人体体素模型外,还经常使用代表较小的异质解剖特征的模型;例如,包含脂肪和纤维腺组织的局部乳腺体素模型已被开发用于各种EM应用,包括乳房x线摄影模拟和剂量学,磁共振成像(MRI)和超宽带微波成像。然而,考虑到波长效应,在亚微波频率下的乳房电磁建模需要详细的乳房模型与全身体素模型相结合。方法:异质乳房模型的大小适合射频线圈硬件,通过体素挤压修改,并使用体素,组织相关的逻辑运算符融合到全身模型。为了说明这种方法的实用性,我们使用了一个全身模型来进行有限差分时域模拟,该模型集成了各种可用的乳房幻影,这些乳房幻影跨越了代表大多数人口的标准四种组织密度分类。结果:软件库使用体素操作的组合来无缝地调整、修改和融合11个乳房幻影到全身体素模型。该软件在GitHub上公开提供,并链接到MATLAB®Central的文件交换。模拟证实了乳腺幻影中脂肪和纤维腺组织的比例对组织中预计的能量沉积具有重要但可预测的影响。结论:乳房幻影可以被修改,并融合到全身体素模型使用本工作中提出的软件;讨论了用户对开源软件和由此产生的幻影的考虑。此外,研究结果表明,将乳房模型主要模拟为脂肪组织会大大低估具有大量纤维腺组织的女性组织加热的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Automated modification and fusion of voxel models to construct body phantoms with heterogeneous breast tissue: Application to MRI simulations.

Automated modification and fusion of voxel models to construct body phantoms with heterogeneous breast tissue: Application to MRI simulations.

Automated modification and fusion of voxel models to construct body phantoms with heterogeneous breast tissue: Application to MRI simulations.

Automated modification and fusion of voxel models to construct body phantoms with heterogeneous breast tissue: Application to MRI simulations.

Background: Human voxel models incorporating detailed anatomical features are vital tools for the computational evaluation of electromagnetic (EM) fields within the body. Besides whole-body human voxel models, phantoms representing smaller heterogeneous anatomical features are often employed; for example, localized breast voxel models incorporating fatty and fibroglandular tissues have been developed for a variety of EM applications including mammography simulation and dosimetry, magnetic resonance imaging (MRI), and ultra-wideband microwave imaging. However, considering wavelength effects, electromagnetic modeling of the breast at sub-microwave frequencies necessitates detailed breast phantoms in conjunction with whole-body voxel models.

Methods: Heterogeneous breast phantoms are sized to fit within radiofrequency coil hardware, modified by voxel-wise extrusion, and fused to whole-body models using voxel-wise, tissue-dependent logical operators. To illustrate the utility of this method, finite-difference time-domain simulations are performed using a whole-body model integrated with a variety of available breast phantoms spanning the standard four tissue density classifications representing the majority of the population.

Results: The software library uses a combination of voxel operations to seamlessly size, modify, and fuse eleven breast phantoms to whole-body voxel models. The software is publicly available on GitHub and is linked to the file exchange at MATLAB® Central. Simulations confirm the proportions of fatty and fibroglandular tissues in breast phantoms have significant yet predictable implications on projected power deposition in tissue.

Conclusions: Breast phantoms may be modified and fused to whole-body voxel models using the software presented in this work; user considerations for the open-source software and resultant phantoms are discussed. Furthermore, results indicate simulating breast models as predominantly fatty tissue can considerably underestimate the potential for tissue heating in women with substantial fibroglandular tissue.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信