{"title":"假性血小板减少症患者血小板计数和其他血液学参数使用替代抗凝剂:硫酸镁。","authors":"Chidambharam Choccalingam, Rajesh Kanna Nandagopal Radha, Nadella Snigdha","doi":"10.1177/1179545X17705380","DOIUrl":null,"url":null,"abstract":"<p><p>The platelet count, mean platelet volume, and other hematological parameters were compared in blood samples anticoagulated with MgSO<sub>4</sub> and EDTA. A total of 15 samples were taken, and the platelet counts were observed to be significantly high in MgSO<sub>4</sub>-anticoagulated blood samples ranging from 53 × 10<sup>3</sup> to 499 × 10<sup>3</sup>/μL, whereas in EDTA-anticoagulated blood samples, the counts ranged from 10 × 10<sup>3</sup> to 353 × 10<sup>3</sup>/μL. This increased platelet count was also statistically significant with the <i>P</i> value being .005. The morphology of red blood cells and white blood cells in Leishman-stained smears from MgSO<sub>4</sub>-anticoagulated blood was below average. In conclusion, MgSO<sub>4</sub> can be used as an alternative anticoagulant only to estimate the platelet counts in EDTA-induced pseudothrombocytopenia.</p>","PeriodicalId":43083,"journal":{"name":"Clinical Medicine Insights-Blood Disorders","volume":null,"pages":null},"PeriodicalIF":3.0000,"publicationDate":"2017-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179545X17705380","citationCount":"5","resultStr":"{\"title\":\"Estimation of Platelet Counts and Other Hematological Parameters in Pseudothrombocytopenia Using Alternative Anticoagulant: Magnesium Sulfate.\",\"authors\":\"Chidambharam Choccalingam, Rajesh Kanna Nandagopal Radha, Nadella Snigdha\",\"doi\":\"10.1177/1179545X17705380\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The platelet count, mean platelet volume, and other hematological parameters were compared in blood samples anticoagulated with MgSO<sub>4</sub> and EDTA. A total of 15 samples were taken, and the platelet counts were observed to be significantly high in MgSO<sub>4</sub>-anticoagulated blood samples ranging from 53 × 10<sup>3</sup> to 499 × 10<sup>3</sup>/μL, whereas in EDTA-anticoagulated blood samples, the counts ranged from 10 × 10<sup>3</sup> to 353 × 10<sup>3</sup>/μL. This increased platelet count was also statistically significant with the <i>P</i> value being .005. The morphology of red blood cells and white blood cells in Leishman-stained smears from MgSO<sub>4</sub>-anticoagulated blood was below average. In conclusion, MgSO<sub>4</sub> can be used as an alternative anticoagulant only to estimate the platelet counts in EDTA-induced pseudothrombocytopenia.</p>\",\"PeriodicalId\":43083,\"journal\":{\"name\":\"Clinical Medicine Insights-Blood Disorders\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2017-04-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1177/1179545X17705380\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Medicine Insights-Blood Disorders\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/1179545X17705380\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2017/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Medicine Insights-Blood Disorders","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/1179545X17705380","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2017/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
Estimation of Platelet Counts and Other Hematological Parameters in Pseudothrombocytopenia Using Alternative Anticoagulant: Magnesium Sulfate.
The platelet count, mean platelet volume, and other hematological parameters were compared in blood samples anticoagulated with MgSO4 and EDTA. A total of 15 samples were taken, and the platelet counts were observed to be significantly high in MgSO4-anticoagulated blood samples ranging from 53 × 103 to 499 × 103/μL, whereas in EDTA-anticoagulated blood samples, the counts ranged from 10 × 103 to 353 × 103/μL. This increased platelet count was also statistically significant with the P value being .005. The morphology of red blood cells and white blood cells in Leishman-stained smears from MgSO4-anticoagulated blood was below average. In conclusion, MgSO4 can be used as an alternative anticoagulant only to estimate the platelet counts in EDTA-induced pseudothrombocytopenia.
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