面部皮肤误用皮质类固醇。一项针对200名患者的研究。

Rohini Sharma, Sameer Abrol, Mashqoor Wani
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引用次数: 23

摘要

背景:外用皮质类固醇已成为非处方药,并被广泛滥用于各种情况。目的:本研究的目的是评估面部皮肤不合理使用局部皮质类固醇的临床和流行病学方面。方法:选取200例面部皮肤病患者,每日面部局部误用皮质类固醇治疗不少于30天。这是在查谟地区的三级护理皮肤科门诊中心进行的一项前瞻性研究。详细的临床病史关于局部使用皮质类固醇和不良反应分析。结果:女性166例,男性34例。年龄以31 ~ 40岁为主。170例患者(85%)年龄在21-50岁之间。申请期限由1个月至3年不等,每日一次。75例(37.5%)患者使用倍他米松或氯倍他索软膏,15例(7.5%)患者使用莫他松。使用类固醇的适应症为:一般/美容目的(72例;36.0%),痤疮(59;29.5%),色素沉着(41;20.5%),癣(6;3%),未确诊的皮肤病(28%;14.0%)。使用皮质类固醇可归因于药剂师的建议(69;34.5%),亲朋好友(61;30.5%)、美容师(22%;11.0%),非皮肤科医生(30;15.0%)和皮肤科医生(18%;9%)。不良反应包括痤疮样病变,智力扩张,色素沉着,多毛,口周皮炎和隐匿性足癣。89例(44.5%)患者符合“局部类固醇依赖面部”标准。这些患者在停止局部使用皮质类固醇后报告出现红斑、灼烧和瘙痒。结论:在大多数情况下,非专业人员推荐长期使用面部皮肤局部皮质类固醇。不良反应从短暂到永久不等。这项研究的结果强调了皮肤科专家在诊断和治疗皮肤疾病中不可或缺的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Misuse of topical corticosteroids on facial skin. A study of 200 patients.

Background: Topical corticosteroids have become available as over the counter drugs and are widely misused for various conditions.

Objective: The aim of this study is to assess the clinical and epidemiological aspects of the unjustified use of topical corticosteroids for facial skin.

Methods: A total of 200 patients with facial dermatoses and topical corticosteroid misapplication daily over face for not less than 30 days were included in the study. This was a prospective study conducted in a tertiary care dermatology outpatient centre of the Jammu region. A detailed clinical history regarding topical corticosteroid use was taken and adverse effects analysed.

Results: A total of 166 patients were women and 34 were men. The predominant age was 31-40 years. A total of 170 patients (85%) were in the age group of 21-50 years. Duration of application was over 1 month up to 3 years, daily. Betamethasone or clobetasol ointments were used in 75 patients (37.5%) and momatasone was used in 15 patients (7.5%). Indication for using steroids were: general / cosmetic purposes (72 patients; 36.0%), acne (59; 29.5%), hyperpigmentation (41; 20.5%), tinea (6; 3%), undiagnosed dermatoses (28; 14.0%). The use of corticosteroids was attributed to the advice of pharmacists (69; 34.5%), friends and relatives (61; 30.5%), cosmetologists (22; 11.0%), non-dermatology physicians (30; 15.0%) and dermatologists (18; 9%). Adverse effects included acneiform lesions, telengiectasias, dyspigmentation, hypertrichosis, perioral dermatitis and tinea incognito. A total of 89 (44.5%) patients fulfilled the criteria of "topical steroid dependent face". These patients reported erythema, burning and itching on stopping the application of topical corticosteroids.

Conclusion: In most cases the use prolonged use of topical corticosteroids on facial skin was recommended by non-professional persons. The adverse events ranged from transient to permanent. The results of this study underline the indispensable role of dermatology specialists in diagnosing and treating cutaneous disorders.

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