科威特单一中心的临床实践审计:儿童持续皮下胰岛素输注和心血管危险因素筛查的管理。

The Open Cardiovascular Medicine Journal Pub Date : 2017-02-28 eCollection Date: 2017-01-01 DOI:10.2174/1874192401711010019
Dina Omar, Hala Alsanae, Mona Al Khawari, Majedah Abdulrasoul, Zahraa Rahme, Faisal Al Refaei, Kazem Behbehani, Azza Shaltout
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引用次数: 4

摘要

目的:审查目前在科威特一个中心接受持续皮下胰岛素输注(CSII)治疗1型糖尿病(T1D)的儿童和青少年的临床实践。方法:对2012年在Dasman糖尿病研究所儿科糖尿病门诊就诊的CSII型T1D儿童和青少年进行为期一年的回顾性审计。主要结局指标为糖化血红蛋白(HbA1c)水平所证明的血糖控制,次要结局指标为微血管并发症风险监测频率、急性并发症和不良事件发生频率。结果:纳入58例儿童和青少年(平均年龄±SD: 12.6±4.1岁)。12个月的观察期结束时,基线时的平均HbA1c为8.8% (72.7 mmol/mol)和8.9% (73.8 mmol/mol)。控制不良的儿童(HbA1c >9.5% (80 mmol/mol))的HbA1c显著降低1.4%,而总体降低0.1% (p=0.7)。心血管危险因素和长期并发症的筛查率有很好的记录。然而,严重低血糖和糖尿病酮症酸中毒等急性并发症的报道不足。只有1.7%的患者停止使用泵。结论:随访12个月后,HbA1c值无明显变化。然而,控制不良儿童的HbA1c值有所改善。CSII需要熟练的保健专业人员的照料,以及教育和选择有积极性的父母和儿童。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

An Audit of Clinical Practice in a Single Centre in Kuwait: Management of Children on Continuous Subcutaneous Insulin Infusion and Cardiovascular Risk Factors Screening.

An Audit of Clinical Practice in a Single Centre in Kuwait: Management of Children on Continuous Subcutaneous Insulin Infusion and Cardiovascular Risk Factors Screening.

An Audit of Clinical Practice in a Single Centre in Kuwait: Management of Children on Continuous Subcutaneous Insulin Infusion and Cardiovascular Risk Factors Screening.

An Audit of Clinical Practice in a Single Centre in Kuwait: Management of Children on Continuous Subcutaneous Insulin Infusion and Cardiovascular Risk Factors Screening.

Objectives: To audit the current clinical practice of continuous subcutaneous insulin infusion (CSII) for the treatment of type 1 diabetes mellitus (T1D) in children and adolescents attending a single centre in Kuwait.

Methods: A one year retrospective audit was performed in children and adolescents with T1D on CSII, who attended the paediatric diabetes clinic, Dasman Diabetes Institute during 2012. The primary outcome measure was glycaemic control as evidenced by glycated haemoglobin (HbA1c) level and the secondary outcome measures were the frequency of monitoring of the risk for microvascular complications and occurrence of acute complications and adverse events.

Results: 58 children and adolescents (mean age ± SD: 12.6 ± 4.1 years) were included. Mean HbA1c at baseline was 8.8% (72.7 mmol/mol) and 8.9% (73.8 mmol/mol) at the end of a 12 months observation period. Children with poor control (HbA1c >9.5% (80 mmol/mol) had a significant 1.4% reduction in HbA1c compared with the overall reduction of 0.1% (p=0.7). Rate of screening for cardiovascular risk factors and for long term complications were well documented. However, there was underreporting of acute complications such as severe hypoglycaemia and diabetic ketoacidosis. Only 1.7% of patients discontinued the pump.

Conclusion: There was no significant change in HbA1c values at the end of 12 months follow up. However, HbA1c values in poorly controlled children improved. CSII requires care by skilled health professionals as well as education and selection of motivated parents and children.

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