拉莫三嗪相关的假性淋巴瘤表现为宫颈淋巴结病

Eoin Mulroy, Elizabeth Walker
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引用次数: 6

摘要

免疫介导的药物反应是抗癫痫药物潜在的危及生命的并发症。药物过敏综合征(DHS)是其中最容易识别的,表现为发烧、嗜酸性粒细胞增多、皮疹和内脏受累。孤立性淋巴结病是一种较少被认识到的免疫介导的抗癫痫药物反应,如拉莫三嗪。我们描述了一个24岁的妇女谁发展拉莫三嗪相关的双侧宫颈淋巴结病(假性淋巴瘤)15个月后治疗开始的情况。这是医学文献中报道的第二例此类病例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Lamotrigine-related pseudolymphoma presenting as cervical lymphadenopathy

Lamotrigine-related pseudolymphoma presenting as cervical lymphadenopathy

Immune-mediated drug reactions are a potentially life-threatening complication of antiseizure medications. Drug hypersensitivity syndrome (DHS) is the best recognised of these, presenting with fever, eosinophilia, rash and internal organ involvement. Isolated lymphadenopathy is a less recognized immune-mediated reaction to antiseizure drugs such as lamotrigine. We describe the case of a 24-year-old woman who developed lamotrigine-related bilateral cervical lymphadenopathy (pseudolymphoma) fifteen months following therapy initiation. This is the second such case reported in the medical literature.

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