{"title":"在临床环境中利用多重技术测量循环细胞因子和免疫激活标记物：我们到底在测量什么？","authors":"Najib Aziz","doi":"10.1615/ForumImmunDisTher.2015014162","DOIUrl":null,"url":null,"abstract":"<p><p>Measurement of circulating cytokine levels can provide important information in the study of the pathogenesis of disease. John L. Fahey was a pioneer in the measurement of circulating cytokines and immune-activation markers and a leader in the quality assessment/control of assays for measurement of circulating cytokines. Insights into the measurement of circulating cytokines, including consideration of multiplex assays, are presented here.</p>","PeriodicalId":89370,"journal":{"name":"Forum on immunopathological diseases and therapeutics","volume":"6 1-2","pages":"19-22"},"PeriodicalIF":0.0000,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345938/pdf/nihms852965.pdf","citationCount":"0","resultStr":"{\"title\":\"Measurement of Circulating Cytokines and Immune-Activation Markers by Multiplex Technology in the Clinical Setting: What Are We Really Measuring?\",\"authors\":\"Najib Aziz\",\"doi\":\"10.1615/ForumImmunDisTher.2015014162\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Measurement of circulating cytokine levels can provide important information in the study of the pathogenesis of disease. John L. Fahey was a pioneer in the measurement of circulating cytokines and immune-activation markers and a leader in the quality assessment/control of assays for measurement of circulating cytokines. Insights into the measurement of circulating cytokines, including consideration of multiplex assays, are presented here.</p>\",\"PeriodicalId\":89370,\"journal\":{\"name\":\"Forum on immunopathological diseases and therapeutics\",\"volume\":\"6 1-2\",\"pages\":\"19-22\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345938/pdf/nihms852965.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Forum on immunopathological diseases and therapeutics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1615/ForumImmunDisTher.2015014162\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Forum on immunopathological diseases and therapeutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1615/ForumImmunDisTher.2015014162","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
循环细胞因子水平的测量可为疾病发病机制的研究提供重要信息。约翰-法黑（John L. Fahey）是循环细胞因子和免疫激活标记物测量的先驱，也是循环细胞因子测量化验质量评估/控制的领导者。本文介绍了对循环细胞因子测量的见解，包括对多重检测方法的考虑。
Measurement of Circulating Cytokines and Immune-Activation Markers by Multiplex Technology in the Clinical Setting: What Are We Really Measuring?
Measurement of circulating cytokine levels can provide important information in the study of the pathogenesis of disease. John L. Fahey was a pioneer in the measurement of circulating cytokines and immune-activation markers and a leader in the quality assessment/control of assays for measurement of circulating cytokines. Insights into the measurement of circulating cytokines, including consideration of multiplex assays, are presented here.
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