轻度肌萎缩侧索硬化症患者的网膜移植。

American journal of neurodegenerative disease Pub Date : 2016-07-06 eCollection Date: 2016-01-01
Hernando Rafael
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引用次数: 0

摘要

证明肌萎缩性侧索硬化症(ALS)不是一种神经退行性疾病。患者33岁,男性,开始时出现球型ALS的症状,特征是两个月的双脚灼痛,然后出现右脚单斜度,束状肌痉挛,轻微构音障碍,并借助矫形装置行走。术前MRI扫描显示左椎动脉V4段动脉粥样硬化。2012年5月,患者接受延髓前、左外侧和后表面大网膜移植。术后约48小时,构音障碍消失,右脚自主运动能力改善。三天后,他不用矫形器就能走路了。目前,手术后四年,他的症状完全逆转。在conclusión中,该患者证实球型ALS是缺血性的,因此,轻度ALS是可以治愈的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Omental transplantation in a patient with mild ALS.

Omental transplantation in a patient with mild ALS.

To demonstrate that amyotrophic lateral sclerosis (ALS) is not a neurodegenerative disease. The patient, a 33-year-old man began with symptoms of the bulbar form of ALS, characterized by burning pain in both feet during two months and then, he presented right crural monoparesis, fasciculations, slight dysarthria and he walked with help of orthopedic devices. A preoperative MRI scans showed atherosclerosis at the V4 segment of the left vertebral artery. On May 2012, he received an omental transplantation on the anterior, left lateral and posterior surface of the medulla oblongata. About 48 hours after surgery, the dysarthria disappeared and the voluntary movement of the right foot improved. Three days later, he walked without aid of orthopedic device. At present, four years after operation he present complete reversal of symptoms. In conclusión, this patient confirms that bulbar ALS is of ischemic origin and therefore, mild ALS can be cured.

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