青少年特发性脊柱侧凸:神经和肌肉病因的当前概念。

Q1 Medicine

Scoliosis and Spinal Disorders Pub Date : 2016-06-27 eCollection Date: 2016-01-01 DOI:10.1186/s13013-016-0066-y

Marcelo Wajchenberg, Nelson Astur, Michel Kanas, Délio Eulálio Martins

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引用次数: 45

摘要

青少年特发性脊柱侧凸是一种常见病，但其病因尚不清楚。女性中的性别患病率已经是已知的，有许多假设可以解释其起源和表现，如相关的神经、肌肉和结缔组织疾病。文献报道试图分析疾病在选定人群中的患病率，可能的遗传方式，相关基因的定位及其多态性，这些可能在畸形的发展中起作用。本文的目的是回顾和更新有关AIS的起源和遗传影响的概念。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Adolescent idiopathic scoliosis: current concepts on neurological and muscular etiologies.

Adolescent idiopathic scoliosis (AIS) is a frequent disease but its etiology remains unknown. Gender prevalence in females is already known and there are many suggested hypotheses to explain its origin and manifestation, like associated neurologic, muscular and connective tissue disorders. Literature reports have tried to analyze disease prevalence in selected populations, possible ways of inheritance, related genes location and their polymorphisms, which may play a role in the development of the deformity. The purpose of this paper is to review and update concepts on the origin and genetic influence on AIS.

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来源期刊

Scoliosis and Spinal Disorders Medicine-Orthopedics and Sports Medicine

CiteScore

5.60

自引率

0.00%

发文量

期刊介绍： Cessation.Scoliosis and Spinal Disorders is an open access, multidisciplinary journal that encompasses all aspects of research on prevention, diagnosis, treatment, outcomes and cost-analyses of conservative and surgical management of all spinal deformities and disorders. Both clinical and basic science reports form the cornerstone of the journal in its endeavour to provide original, primary studies as well as narrative/systematic reviews and meta-analyses to the academic community and beyond. Scoliosis and Spinal Disorders aims to provide an integrated and balanced view of cutting-edge spine research to further enhance effective collaboration among clinical spine specialists and scientists, and to ultimately improve patient outcomes based on an evidence-based spine care approach.