{"title":"评估镍的释放从各种牙科器具常规使用在儿科牙科。","authors":"Parimala Kulkarni, Suchi Agrawal, Arpana Bansal, Ankur Jain, Utkarsh Tiwari, Ayushi Anand","doi":"10.4103/0975-962X.184649","DOIUrl":null,"url":null,"abstract":"<p><strong>Context: </strong>The use of nickel-containing alloys in dentistry has been questioned because of the biological liabilities of nickel and the release of nickel ions from dental appliances into the oral cavity. The potential health hazards of nickel and chromium and their compounds have been the focus of attention for more than 100 years. It has established that these metals could cause hypersensitivity.</p><p><strong>Aims: </strong>To assess the nickel release from various dental appliances used in pediatric dentistry.</p><p><strong>Settings and design: </strong>It is a in vitro study.</p><p><strong>Materials and methods: </strong>The study was undertaken to analyze in vitro biodegradation of space maintainers and stainless steel crowns made out of stainless steel materials from different manufacturers. The leaching effect simulating the use of clinical practice was studied by keeping the respective number of Stainless Steel Crowns and space maintainers in the artificial saliva incubating at 37°C and analyzing for nickel release after 1,7,14,21 and 28 days using atomic absorption spectrophotometer.</p><p><strong>Statistical analysis: </strong>The results were statistically analyzed by using One way ANOVA and repeated measures of ANOVA was applied at different time intervals i.e. 1,7,14,21,28 days. The critical value for statistical significance was set at P = 0.05.</p><p><strong>Results: </strong>Results showed that there was measurable release of nickel which reached maximum level at the end of 7 days which was statistically significant (P < 0.05).</p><p><strong>Conclusions: </strong>The release of nickel and chromium very much below when compared with the average dietary intake of nickel (200-300 ppm/day) which were not capable of causing any toxic effects.</p>","PeriodicalId":90526,"journal":{"name":"Indian journal of dentistry","volume":"7 2","pages":"81-5"},"PeriodicalIF":0.0000,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6d/ac/IJDENT-7-81.PMC4934093.pdf","citationCount":"17","resultStr":"{\"title\":\"Assessment of nickel release from various dental appliances used routinely in pediatric dentistry.\",\"authors\":\"Parimala Kulkarni, Suchi Agrawal, Arpana Bansal, Ankur Jain, Utkarsh Tiwari, Ayushi Anand\",\"doi\":\"10.4103/0975-962X.184649\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Context: </strong>The use of nickel-containing alloys in dentistry has been questioned because of the biological liabilities of nickel and the release of nickel ions from dental appliances into the oral cavity. The potential health hazards of nickel and chromium and their compounds have been the focus of attention for more than 100 years. It has established that these metals could cause hypersensitivity.</p><p><strong>Aims: </strong>To assess the nickel release from various dental appliances used in pediatric dentistry.</p><p><strong>Settings and design: </strong>It is a in vitro study.</p><p><strong>Materials and methods: </strong>The study was undertaken to analyze in vitro biodegradation of space maintainers and stainless steel crowns made out of stainless steel materials from different manufacturers. The leaching effect simulating the use of clinical practice was studied by keeping the respective number of Stainless Steel Crowns and space maintainers in the artificial saliva incubating at 37°C and analyzing for nickel release after 1,7,14,21 and 28 days using atomic absorption spectrophotometer.</p><p><strong>Statistical analysis: </strong>The results were statistically analyzed by using One way ANOVA and repeated measures of ANOVA was applied at different time intervals i.e. 1,7,14,21,28 days. 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引用次数: 17
摘要
背景:含镍合金在牙科中的使用一直受到质疑,因为镍的生物责任和从牙科器具释放的镍离子进入口腔。100多年来,镍和铬及其化合物对健康的潜在危害一直是人们关注的焦点。已经确定这些金属会导致过敏。目的:评估儿童牙科中使用的各种牙科器具对镍的释放。环境和设计:这是一项体外研究。材料与方法:对不同厂家不锈钢材料制成的空间维持器和不锈钢冠进行体外生物降解分析。在37℃人工唾液中分别保留不同数量的不锈钢牙冠和空间维持器,并在1、7、14、21和28天后用原子吸收分光光度计分析镍的释放量,模拟临床应用,研究其浸出效果。统计分析:采用单因素方差分析(One - way ANOVA)对结果进行统计分析,并在不同的时间间隔(1、7、14、21、28天)采用方差分析的重复测量。P = 0.05为具有统计学意义的临界值。结果:镍的释放量可测,7 d时达到最大值,差异有统计学意义(P < 0.05)。结论:镍和铬的释放量远远低于镍的平均膳食摄入量(200-300 ppm/天),不会引起任何毒性作用。
Assessment of nickel release from various dental appliances used routinely in pediatric dentistry.
Context: The use of nickel-containing alloys in dentistry has been questioned because of the biological liabilities of nickel and the release of nickel ions from dental appliances into the oral cavity. The potential health hazards of nickel and chromium and their compounds have been the focus of attention for more than 100 years. It has established that these metals could cause hypersensitivity.
Aims: To assess the nickel release from various dental appliances used in pediatric dentistry.
Settings and design: It is a in vitro study.
Materials and methods: The study was undertaken to analyze in vitro biodegradation of space maintainers and stainless steel crowns made out of stainless steel materials from different manufacturers. The leaching effect simulating the use of clinical practice was studied by keeping the respective number of Stainless Steel Crowns and space maintainers in the artificial saliva incubating at 37°C and analyzing for nickel release after 1,7,14,21 and 28 days using atomic absorption spectrophotometer.
Statistical analysis: The results were statistically analyzed by using One way ANOVA and repeated measures of ANOVA was applied at different time intervals i.e. 1,7,14,21,28 days. The critical value for statistical significance was set at P = 0.05.
Results: Results showed that there was measurable release of nickel which reached maximum level at the end of 7 days which was statistically significant (P < 0.05).
Conclusions: The release of nickel and chromium very much below when compared with the average dietary intake of nickel (200-300 ppm/day) which were not capable of causing any toxic effects.