{"title":"冠状动脉疾病患者颈股脉波速度与冠心病之间是否存在关联:一项初步研究","authors":"Niki Katsiki, Erietta Kollari, Sotirios Dardas, Petros Dardas, Anna-Bettina Haidich, Vasilios G Athyros, Asterios Karagiannis","doi":"10.2174/1874192401610010064","DOIUrl":null,"url":null,"abstract":"<p><p>Arterial stiffness has been shown to predict cardiovascular morbidity and mortality. Carotid-femoral pulse wave velocity (cfPWV) is regarded the gold standard marker of arterial stiffness. In previous studies, cfPWV was associated with the presence of coronary heart disease (CHD). However, with regard to CHD severity as assessed by the Syntax Score, only brachial-ankle PWV was reported to correlate with Syntax Score; no data exist for cfPWV. In this pilot study, we evaluated the possible associations between cfPWV, CHD and Syntax Score in 62 consecutive pa-tients (49 males; mean age: 64±12years) with chest pain undergoing scheduled coronary angiography. cfPWV was signifi-cantly higher in CHD patients than in non-CHD individuals (10 vs. 8.4 m/s; p = 0.003). No significant association was found between cfPWV and CHD severity as assessed by Syntax Score. A cut-off point of 12.3 m/s was considered as diagnostic for abnormally increased cfPWV (specificity: 97%; sensitivity: 12%; positive likelihood ratio: 3.558). Further research is needed to establish the relationship between cfPWV and Syntax Score. </p>","PeriodicalId":504447,"journal":{"name":"The Open Cardiovascular Medicine Journal","volume":"10 ","pages":"64-8"},"PeriodicalIF":0.0000,"publicationDate":"2016-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/df/de/TOCMJ-10-64.PMC4896998.pdf","citationCount":"5","resultStr":"{\"title\":\"Is There an Association Between Carotid-Femoral Pulse Wave Velocity and Coronary Heart Disease in Patients with Coronary Artery Disease: A Pilot Study.\",\"authors\":\"Niki Katsiki, Erietta Kollari, Sotirios Dardas, Petros Dardas, Anna-Bettina Haidich, Vasilios G Athyros, Asterios Karagiannis\",\"doi\":\"10.2174/1874192401610010064\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Arterial stiffness has been shown to predict cardiovascular morbidity and mortality. Carotid-femoral pulse wave velocity (cfPWV) is regarded the gold standard marker of arterial stiffness. In previous studies, cfPWV was associated with the presence of coronary heart disease (CHD). However, with regard to CHD severity as assessed by the Syntax Score, only brachial-ankle PWV was reported to correlate with Syntax Score; no data exist for cfPWV. In this pilot study, we evaluated the possible associations between cfPWV, CHD and Syntax Score in 62 consecutive pa-tients (49 males; mean age: 64±12years) with chest pain undergoing scheduled coronary angiography. cfPWV was signifi-cantly higher in CHD patients than in non-CHD individuals (10 vs. 8.4 m/s; p = 0.003). No significant association was found between cfPWV and CHD severity as assessed by Syntax Score. A cut-off point of 12.3 m/s was considered as diagnostic for abnormally increased cfPWV (specificity: 97%; sensitivity: 12%; positive likelihood ratio: 3.558). Further research is needed to establish the relationship between cfPWV and Syntax Score. </p>\",\"PeriodicalId\":504447,\"journal\":{\"name\":\"The Open Cardiovascular Medicine Journal\",\"volume\":\"10 \",\"pages\":\"64-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-05-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/df/de/TOCMJ-10-64.PMC4896998.pdf\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Open Cardiovascular Medicine Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1874192401610010064\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2016/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Open Cardiovascular Medicine Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1874192401610010064","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2016/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
摘要
动脉硬度已被证明可以预测心血管疾病的发病率和死亡率。颈-股脉波速度(cfPWV)被认为是动脉硬度的金标准指标。在以前的研究中,cfPWV与冠心病(CHD)的存在有关。然而,就句法评分评估的冠心病严重程度而言,只有肱-踝PWV被报道与句法评分相关;cfPWV数据不存在。在这项初步研究中,我们评估了62例连续患者(49例男性;平均年龄:64±12岁)胸痛行冠脉造影。冠心病患者的cfPWV显著高于非冠心病患者(10 vs. 8.4 m/s;P = 0.003)。句法评分显示,cfPWV与冠心病严重程度无显著相关性。12.3 m/s被认为是诊断cfPWV异常升高的截断点(特异性:97%;灵敏度:12%;正似然比:3.558)。cfPWV与句法评分之间的关系有待进一步研究。
Is There an Association Between Carotid-Femoral Pulse Wave Velocity and Coronary Heart Disease in Patients with Coronary Artery Disease: A Pilot Study.
Arterial stiffness has been shown to predict cardiovascular morbidity and mortality. Carotid-femoral pulse wave velocity (cfPWV) is regarded the gold standard marker of arterial stiffness. In previous studies, cfPWV was associated with the presence of coronary heart disease (CHD). However, with regard to CHD severity as assessed by the Syntax Score, only brachial-ankle PWV was reported to correlate with Syntax Score; no data exist for cfPWV. In this pilot study, we evaluated the possible associations between cfPWV, CHD and Syntax Score in 62 consecutive pa-tients (49 males; mean age: 64±12years) with chest pain undergoing scheduled coronary angiography. cfPWV was signifi-cantly higher in CHD patients than in non-CHD individuals (10 vs. 8.4 m/s; p = 0.003). No significant association was found between cfPWV and CHD severity as assessed by Syntax Score. A cut-off point of 12.3 m/s was considered as diagnostic for abnormally increased cfPWV (specificity: 97%; sensitivity: 12%; positive likelihood ratio: 3.558). Further research is needed to establish the relationship between cfPWV and Syntax Score.