[发光光细菌磷、大肠杆菌和枯草芽孢杆菌菌株对碳基纳米材料和金属纳米颗粒毒性作用的比较敏感性]。

Mikrobiologiia Pub Date : 2016-03-01
D G Deryabina, L V Efremova, I F Karimov, I V Manukhov, E Yu Gnuchikh, S A Miroshnikov
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引用次数: 0

摘要

本研究比较分析了四种市售和实验室发光传感器菌株对10种碳基纳米材料(CBNs)和10种金属纳米颗粒(MNPs)的毒性作用。海洋磷光杆菌和重组大肠杆菌菌株的生物发光抑制试验在最小毒性浓度和EC50值上存在差异,但其生物毒性评价相关性较好,活性化合物为Cu > (MgO, CuO) >(富勒烯醇,氧化石墨烯)。新型传感器菌株枯草芽孢杆菌(Bacillus subtilis) EG 168-1对CBNs和MNPs的敏感性最高,可以显著增加引起细菌生物发光抑制作用的有毒化合物的数量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Comparative Sensitivity of the Luminescent Photobacterium phosphoreum, Escherichia coli, and Bacillus subtilis Strains to Toxic Effects of Carbon-Based Nanomaterials and Metal Nanoparticles].

A comparative analysis of the four commercially available and laboratory luminescent sensor strains to the toxic effect of 10 carbon-based nanomatherials (CBNs) and 10 metal nanoparticles (MNPs) was carried out in this study. The bioluminescence inhibition assays with marine Photobacterium phosphoreum and recombinant Escherichia coli strains were varied in minimal toxic concentrations and EC50 values but led to well correlated biotoxicity evaluation for the most active compounds were ranked as Cu > (MgO, CuO) > (fullerenol, graphene oxide). The novel sensor strain Bacillus subtilis EG 168-1 exhibited the highest sensitivity to CBNs and MNPs that increased significantly number of toxic compounds causing the bacterial bioluminescence inhibition effect.

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