职业暴露对甲型H1N1流感pdm09感染及住院的影响

Annals of Occupational Hygiene Pub Date : 2016-10-01 Epub Date: 2016-07-18 DOI:10.1093/annhyg/mew044
Jesús Pujol, Pere Godoy, Núria Soldevila, Jesús Castilla, Fernando González-Candelas, Jose M Mayoral, Jenaro Astray, Susana García, Vicente Martín, Sonia Tamames, Miguel Delgado, Ángela Domínguez García
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引用次数: 3

摘要

目的:分析西班牙2009-2010年流感大流行和2010-2011年流感季节性流行期间职业暴露与流感感染和住院的关系。方法:将职业分为高、中、低流感暴露风险。为评估感染风险,将588例经逆转录聚合酶链反应(RT-PCR)确诊的门诊流感患者与588例无流感症状的门诊患者进行比较。为了评估住院风险,将337例门诊流感病例与337例住院流感病例进行比较。结果:职业暴露高危人群仅为医护人员。在调整了年龄、性别、疫苗接种状况和流感感染的预测变量后,与低风险患者相比,职业暴露高风险患者成为门诊流感病例的aOR为2.14 (95%CI: 1.25-3.66),成为住院流感病例的aOR为0.43 (95%CI: 0.20-0.95)。结论:高职业暴露风险是流感感染的危险因素,但不是住院的危险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Occupational Exposure on A(H1N1)pdm09 Infection and Hospitalization.

Objective: To analyze relationships between occupational exposure and influenza infection and hospitalization during the 2009-2010 pandemic wave and the 2010-2011 influenza seasonal epidemic in Spain.

Methods: Occupations were classified as high, medium, or low risk of influenza exposure. To assess the risk of infection, 588 outpatient cases of influenza confirmed by reverse-transcription polymerase-chain-reaction (RT-PCR) were compared with 588 outpatients without influenza symptoms. To assess the risk of hospitalization, 337 outpatient influenza cases were compared with 337 inpatient influenza cases.

Results: The high risk of occupational exposure group was composed only of health care workers. After adjustment for age, sex, vaccination status, and predictive variables of influenza infection, patients with a high risk of occupational exposure had an aOR of 2.14 (95%CI: 1.25-3.66) of being an outpatient influenza case and an aOR of 0.43 (95%CI: 0.20-0.95) of being an inpatient influenza case, compared with those with a low risk.

Conclusions: A high risk of occupational exposure is a risk factor for influenza infection but not for hospitalization.

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