苏云杜松(Juniperus thurifera(L.))、氧化木(J.oxidedrus(L.)、凤凰木(J.phoenicea(L.)和牙鲆(Tetraclinis articulata(L.)的清除自由基活性和铁还原能力。

Q1 Pharmacology, Toxicology and Pharmaceutics
Advances in Pharmacological Sciences Pub Date : 2016-01-01 Epub Date: 2016-05-16 DOI:10.1155/2016/6392656
Meryem El Jemli, Rabie Kamal, Ilias Marmouzi, Asmae Zerrouki, Yahia Cherrah, Katim Alaoui
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引用次数: 95

摘要

目标。研究并比较了产自摩洛哥的thurifera、Juniperus oxycedrus、Juniperus Phoenicea和Tetraclinis articulata叶提取物的抗氧化性能和酚类物质含量。方法。通过2,2-二苯基-1-苦基肼基(DPPH)自由基清除能力、Trolox等效抗氧化能力(TEAC)和铁还原抗氧化能力(FRAP)测定评价提取物的抗氧化活性。用分光光度法测定了提取物中总酚和总黄酮的含量。结果。与标准抗氧化剂(丁基羟基甲苯(BHT)、槲皮素和Trolox)相比,所有提取物都显示出有趣的抗氧化活性。DPPH、TEAC和FRAP测定结果显示,杜松水提物的抗氧化活性最高,IC50值分别为17.91±0.37 μg/mL、19.80±0.55 μg/mL和24.23±0.07 μg/mL。抗氧化能力与其总酚含量之间的相关性表明,酚类化合物是这些植物提取物抗氧化性能的主要贡献者。结论。上述结果表明,沙棘杜松、氧化杜松、凤凰杜松和关节四环木的水提物是一种具有抗氧化能力的天然化合物的新来源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Radical-Scavenging Activity and Ferric Reducing Ability of Juniperus thurifera (L.), J. oxycedrus (L.), J. phoenicea (L.) and Tetraclinis articulata (L.).

Radical-Scavenging Activity and Ferric Reducing Ability of Juniperus thurifera (L.), J. oxycedrus (L.), J. phoenicea (L.) and Tetraclinis articulata (L.).

Radical-Scavenging Activity and Ferric Reducing Ability of Juniperus thurifera (L.), J. oxycedrus (L.), J. phoenicea (L.) and Tetraclinis articulata (L.).

Objective. The aim of this work is to study and compare the antioxidant properties and phenolic contents of aqueous leaf extracts of Juniperus thurifera, Juniperus oxycedrus, Juniperus Phoenicea, and Tetraclinis articulata from Morocco. Methods. Antioxidant activities of the extracts were evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical-scavenging ability, Trolox equivalent antioxidant capacity (TEAC), and ferric reducing antioxidant power (FRAP) assays. Also the total phenolic and flavonoids contents of the extracts were determined spectrophotometrically. Results. All the extracts showed interesting antioxidant activities compared to the standard antioxidants (butylated hydroxytoluene (BHT), quercetin, and Trolox). The aqueous extract of Juniperus oxycedrus showed the highest antioxidant activity as measured by DPPH, TEAC, and FRAP assays with IC50 values of 17.91 ± 0.37 μg/mL, 19.80 ± 0.55 μg/mL, and 24.23 ± 0.07 μg/mL, respectively. The strong correlation observed between antioxidant capacities and their total phenolic contents indicated that phenolic compounds were a major contributor to antioxidant properties of these plants extracts. Conclusion. These results suggest that the aqueous extracts of Juniperus thurifera, Juniperus oxycedrus, Juniperus phoenicea, and Tetraclinis articulata can constitute a promising new source of natural compounds with antioxidants ability.

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来源期刊
Advances in Pharmacological Sciences
Advances in Pharmacological Sciences PHARMACOLOGY & PHARMACY-
CiteScore
6.40
自引率
0.00%
发文量
0
审稿时长
14 weeks
期刊介绍: Advances in Pharmacological and Pharmaceutical Sciences is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies in all areas of experimental and clinical pharmacology, pharmaceutics, medicinal chemistry and drug delivery. Topics covered by the journal include, but are not limited to: -Biochemical pharmacology, drug mechanism of action, pharmacodynamics, pharmacogenetics, pharmacokinetics, and toxicology. -The design and preparation of new drugs, and their safety and efficacy in humans, including descriptions of drug dosage forms. -All areas of medicinal chemistry, such as drug discovery, design and synthesis. -Basic biology of drug and gene delivery through to application and development of these principles, through therapeutic delivery and targeting. Areas covered include bioavailability, controlled release, microcapsules, novel drug delivery systems, personalized drug delivery, and techniques for passing biological barriers.
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