再生医学中的荧光细胞成像。

IF 2.3 Q3 ENGINEERING, BIOMEDICAL
Biomedical Engineering and Computational Biology Pub Date : 2016-05-02 eCollection Date: 2016-01-01 DOI:10.4137/BECB.S39045
Etai Sapoznik, Guoguang Niu, Yu Zhou, Sean V Murphy, Shay Soker
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引用次数: 3

摘要

荧光蛋白成像是生物学研究中一个很有前途的工具,在再生医学领域具有广泛的应用前景。为了加强组织再生的努力,科学家们一直在研究新的方法来监测体外和体内组织的发育和成熟。为此,开发了新的成像工具和新型荧光蛋白,用于进行深部组织高分辨率成像。这些新方法,如生命内显微镜和Förster共振能量转移,为细胞行为提供了新的见解,包括细胞迁移、形态学和动态环境中的表型变化。这些应用与多模态成像相结合,极大地扩展了荧光蛋白成像在再生医学研究和临床应用中的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fluorescent Cell Imaging in Regenerative Medicine.

Fluorescent protein imaging, a promising tool in biological research, incorporates numerous applications that can be of specific use in the field of regenerative medicine. To enhance tissue regeneration efforts, scientists have been developing new ways to monitor tissue development and maturation in vitro and in vivo. To that end, new imaging tools and novel fluorescent proteins have been developed for the purpose of performing deep-tissue high-resolution imaging. These new methods, such as intra-vital microscopy and Förster resonance energy transfer, are providing new insights into cellular behavior, including cell migration, morphology, and phenotypic changes in a dynamic environment. Such applications, combined with multimodal imaging, significantly expand the utility of fluorescent protein imaging in research and clinical applications of regenerative medicine.

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